1.
Semin Dermatol
; 8(2): 85-7, 1989 Jun.
Article
in English
| MEDLINE
| ID: mdl-2641721
2.
Adv Exp Med Biol
; 160: 251-63, 1983.
Article
in English
| MEDLINE
| ID: mdl-6220575
3.
Pharmazie
; 37(6): 395-402, 1982 Jun.
Article
in English
| MEDLINE
| ID: mdl-6750656
4.
Experientia
; 37(11): 1134-7, 1981 Nov 15.
Article
in English
| MEDLINE
| ID: mdl-7318990
ABSTRACT
3-Hydroxyphenylpyruvic acid was oxygenated with various complexes of oxygen with Fe2+, superoxide ion, hydroperoxide anion, triplet and singlet oxygen. Oxidation occurred giving varying amounts of the 4-hydroxy derivatives of benzaldehyde, benzoic acid, phenol, phenylacetic acid and 4-carboxymethylquinone, but no homogentisic acid. 4-Hydroxyphenylperacetic acid was prepared and shown not to undergo self-oxidation. Its ferrous salt decomposed to 4-hydroxybenzyl alcohol. It is concluded that the alpha-keto carboxylic function is the site of oxygenation in the enzyme process and that a trioxalanone rather than a peracid intermediate may be implicated.
Subject(s)
4-Hydroxyphenylpyruvate Dioxygenase/metabolism , Models, Chemical , Oxygenases/metabolism , Iron , Oxygen
5.
Fortschr Chem Org Naturst
; 40: 191-265, 1981.
Article
in English
| MEDLINE
| ID: mdl-7016695