Polybrominated diphenyl ethers (PBDEs) in plasma from E-waste recyclers, outdoor and indoor workers in the Puget Sound, WA region.

Polybrominated diphenyl ethers (PBDEs) were widely used as flame retardants in consumer products including electronic devices. Important routes of human exposure are contaminated food and contact with dust. In this study, we measured twelve PBDEs in household/workplace dust and blood plasma samples provided by 113 volunteers living in the Puget Sound region, WA and working at electronic waste (E-waste) recycling sites (n = 29) or non-specific indoor (n = 57) or outdoor occupations (n = 27). The volunteers in the outdoor group were also selected because of a history of high seafood consumption habits. Results indicated the sum PBDE levels varied between <2.5 and up to 310 ng g-1 lipid. E-waste recyclers were predominantly men, generally consumed low amounts of seafood, and had PBDE blood levels (geometric mean, GM = 26.56 ng g-1 lipid) that were similar to indoor workers (GM = 27.17 ng g-1 lipid). The sum PBDE levels were highest in the outdoor group (GM = 50.63 ng g-1 lipid). Dust samples from E-waste sites were highly enriched with BDE-209 and BDE-153 relative to non-E-waste businesses and homes. The concentrations of these BDE congeners in dust at E-waste sites were ∼32-39 times higher than in dust from other sites. However, the detection rate of BDE-209 in plasma was low across all groups (13%) and no statistical comparisons were made. Our results suggest that E-waste recyclers in this study population did not have elevated PBDE levels in comparison to volunteers working in other types of occupations.

Polybrominated diphenyl ethers and their hydroxylated and methoxylated derivatives in seafood obtained from Puget Sound, WA.

Synthetic polybrominated diphenyl ethers (PBDEs) are ubiquitous environmental contaminants and known to occur in most food items. Consumer fish products have been identified as having some of the highest PBDE levels found in USA food sources. Natural formation of hydroxylated (OH-) and methoxylated (MeO-) PBDEs are also known to occur in simple marine organisms, which may be bioaccumulated by seafood. In this study, we report findings of an initial survey of PBDE, OH-PBDE and MeO-PBDE content in common seafood items available to residents living in the Puget Sound region of Washington State. Seafood samples were either purchased from local grocery stores or caught off the coast of SE Alaska and in Puget Sound. The edible portions of the seafood were analyzed, which for finfish was white muscle (skinless fillets) and for shellfish, either the entire soft tissue (bivalves) or processed meat (calamari, shrimp and scallops). Results indicated that finfish typically had higher levels of PBDEs compared to shellfish with BDE-47 and BDE-99 as the most common congeners detected. Among shellfish, bivalves (clams and mussels) were notable for having much higher levels of OH- and MeO-PBDEs compared to other types of seafood with 6'-OH-BDE-47 and 2'-MeO-BDE-68 being the more common OH- and MeO- congeners, respectively. Based on our results and recent updates to daily fish consumption rates, estimated intake rates for Washington State residents will be between 34 and 644ngPBDEs/day, depending on species consumed. For the OH- and MeO- forms, daily exposure is much more variable but typically would range between 15 and 90ng/day for most seafood types. If shellfish are primarily consumed, OH-PBDE intake could be as high as 350ng/day. These daily intake rates for PBDEs are higher than most dietary intake rates calculated for populations in other world regions.