ABSTRACT
It has been reported that intravaginal culture (IVC) yields results comparable to those obtained with classic IVF techniques; furthermore, it can simplify and reduce the costs of the procedure. In our experience with IVC however, only 8 of 78 mature oocytes inseminated (10.2%) fertilized. Possible causes of this low fertilization rate were analyzed. In our opinion this new and attractive technique needs further evaluation before being extended to common clinical practice.
Subject(s)
Fertilization in Vitro/methods , Fertilization/physiology , Vagina/physiology , Cells, Cultured , Female , Humans , Male , Oocytes/cytology , Oocytes/physiology , Spermatozoa/cytology , Spermatozoa/physiologyABSTRACT
Intrauterine insemination (IUI) was performed on sixty eight couples with a total of 126 cycles between July 1984 and December 1986. 14 pregnancies (20.5% per couple, 11.1% per cycle) were obtained with this therapeutical approach. In 39 couples a male factor was cause of infertility. In this group six pregnancies were obtained in 71 treatment cycles (15.1% per couple, 8.4% per cycle). Sterility due to a cervical factor was treated through IUI in 18 couples during 34 cycles. Six pregnancies (33.3% per couple 17.6% per cycle) were obtained in this group. Unexplained infertility found in 11 couples was treated with IUI in 21 cycles; two pregnancies (18.2% per couple, 9.5% per cycle) were obtained. Most pregnancies in all causes of infertility were obtained in the two first insemination cycles and no pregnancy was obtained after four cycles. Active ovulation induction was performed in the majority of the cases and only one insemination was usually accomplished. The only predictive semen parameter statistically significant in terms of pregnancy in masculine factor, was the total amount of progressive spermatozoa recovered after the washing procedure. In other words, pregnancy in more probable when less spermatozoa are lost during the procedure.
Subject(s)
Infertility/etiology , Insemination, Artificial, Homologous , Pregnancy , Adult , Female , Humans , Male , Sperm MotilityABSTRACT
In a patient carrying a secondary sterility with previous failure of surgical and medical treatment, a pregnancy due to intracorporea fertilization in vaginal culture is obtained. With this system, we avoid the in vitro Fertilization in the laboratory.
Subject(s)
Embryo Transfer , Fertilization , Pregnancy , Adult , Cells, Cultured , Female , Humans , Infertility, Female/therapy , VaginaABSTRACT
En una paciente portadora de una infertilidad secundaria, con fracaso de tratamientos médicos y quirúrgicos; se obtiene un embarazo por fertilización intracorpórea en cultivo vaginal. La vagina actuando como incubadora donde se colocan los gametos, permite esta fertilización en el organismo de la madre, al revés de lo que ocurre en la FIV, donde este proceso inicial se realiza en el laboratorio
