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1.
Semin Immunol ; 25(2): 104-13, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23886895

ABSTRACT

The incidence of dengue has been on the rise since at least the 1960s, bringing greater urgency to the need for a vaccine to prevent the disease. Recent advances suggest that the scientific world is moving closer to an effective dengue vaccine. However, there are concerns that the price of a future vaccine could limit its uptake. High prices, in addition to other challenges, have already weighed negatively in government decisions to include other new vaccines in national immunization programs, e.g., the pneumococcal, rotavirus, and human papillomavirus vaccines. Recent research on the value of vaccination, however, suggests that vaccination confers benefits that are often neglected by traditional economic evaluations. In the case of dengue, commonly overlooked benefits are likely to include reduced spending on outbreak control, averted losses in tourism flows, and avoided productivity losses due to long-term dengue sequelae. Accounting for these and other broader benefits of dengue vaccination could reveal significantly greater economic value and strengthen the case for inclusion of dengue vaccination in national immunization programs. In this article we discuss a framework for the broader value of vaccination and review its application in the context of dengue vaccination for Brazil.


Subject(s)
Dengue Vaccines , Dengue/prevention & control , Animals , Brazil , Cost-Benefit Analysis , Dengue/epidemiology , Humans , Quality Improvement
2.
Acad Radiol ; 19(10): 1268-72, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22958721

ABSTRACT

RATIONALE AND OBJECTIVES: The aim of this study was to explore women's interest and preferences in undergoing screening mammography in a retail health care setting. MATERIALS AND METHODS: Self-administered surveys were distributed to 400 mammography patients in May to June 2009. All of the women who were asked were eligible for screening (age >40 years, no abnormal mammographic findings in the recent past). Three hundred eighty-six screening-eligible women filled out and returned the self-administered survey. RESULTS: The average respondent age was 57 years. Three hundred ten of the patients (80.3%) had college or postgraduate educations. Two hundred three (52.6%) reported annual incomes >$60,000. Two hundred forty-one respondents (62.4%) had been undergoing screening mammography for >10 years, while this was the first examination for eight patients (2%). More than half of the patients (n = 215 [55.7%]) affirmed their interest in undergoing annual screening mammography in a private area within a retail shopping facility. Most preferred a pharmacy (77%) over Wal-Mart or a grocery store. Appealing factors about a retail setting were proximity to home (90%), free parking (62%), and operating hours (48.8%). CONCLUSIONS: There is interest among women in undergoing screening mammography at retail health care clinics, preferably pharmacies. The provision of services at a convenient location can increase adherence to guidelines for screening mammography.


Subject(s)
Breast Neoplasms/diagnostic imaging , Breast Neoplasms/prevention & control , Commerce/statistics & numerical data , Early Detection of Cancer/statistics & numerical data , Mammography/statistics & numerical data , Mass Screening/statistics & numerical data , Patient Preference/statistics & numerical data , Adult , Age Distribution , Aged , Boston/epidemiology , Breast Neoplasms/epidemiology , Educational Status , Female , Humans , Middle Aged , Prevalence , Risk Factors , Socioeconomic Factors , Surveys and Questionnaires , Women's Health , Young Adult
3.
Diabetes Care ; 35(4): 738-40, 2012 Apr.
Article in English | MEDLINE | ID: mdl-22323417

ABSTRACT

OBJECTIVE: The increasing burdens of obesity and diabetes are two of the most prominent threats to the health of populations of developed and developing countries alike. The Central America Diabetes Initiative (CAMDI) is the first study to examine the prevalence of diabetes in Central America. RESEARCH DESIGN AND METHODS: The CAMDI survey was a cross-sectional survey based on a probabilistic sample of the noninstitutionalized population of five Central American populations conducted between 2003 and 2006. The total sample population was 10,822, of whom 7,234 (67%) underwent anthropometry measurement and a fasting blood glucose or 2-h oral glucose tolerance test. RESULTS: The total prevalence of diabetes was 8.5%, but was higher in Belize (12.9%) and lower in Honduras (5.4%). Of the screened population, 18.6% had impaired glucose tolerance/impaired fasting glucose. CONCLUSIONS: As this population ages, the prevalence of diabetes is likely to continue to rise in a dramatic and devastating manner. Preventive strategies must be quickly introduced.


Subject(s)
Diabetes Mellitus/epidemiology , Hyperglycemia/epidemiology , Adult , Aged , Aged, 80 and over , Central America/epidemiology , Cross-Sectional Studies , Diabetes Complications/blood , Diabetes Complications/epidemiology , Diabetes Mellitus/blood , Female , Humans , Hyperglycemia/blood , Hyperglycemia/complications , Internationality , Male , Middle Aged , Prevalence , Severity of Illness Index , Young Adult
4.
Prim Care Diabetes ; 4(3): 145-53, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20478753

ABSTRACT

UNLABELLED: The prevalence of diabetes in Mexico among those 20-64 years of age has increased from 7.2% in 1993 to 10.7% in 2000. National population-based surveys in Mexico demonstrated that 50% of the total population with diabetes had blood glucose levels of 200mg/dl or higher. Thus, diabetes care has become one of the most important public health challenges in this country. The aim of the study was to improve the quality of diabetes care in primary health care centers using the chronic care model and the breakthrough series (BTS) collaborative methodology. METHODS: Ten public health centers in the cities of Xalapa and Veracruz were randomly selected to participate in the project. Five of the health centers were randomly assigned to receive the intervention (intervention group) and the other five followed usual care (usual care group). The intervention was evaluated by A1c test before and after the intervention in both groups of patients. Patients were followed for 18 months from November 2002 to May 2004. Results were adjusted for the clustering of patients within practices and baseline measure. RESULTS: The proportion of people with good glycemic control (A1c<7%) among those in the intervention group increased from 28% before the intervention to 39% after the intervention. The proportion of patients achieving three or more quality improvement goals increased from 16.6% to 69.7% (p<0.001) among the intervention group while the usual care group experienced a non-significant decrease from 12.4% to 5.9% (p=0.118). The focus on the primary care team and the participation of people with diabetes were strategic elements incorporated into the methodology, expected to ensure sustainability of continued improvement of health outcomes. CONCLUSIONS: The intervention introduced modifications to solve problems identified by health teams in their practice and improved process and outcome measures of quality diabetes care. Most of the actions were directed at four components of the chronic care model: self-management support, decision support, delivery system design, and clinical information systems.


Subject(s)
Cooperative Behavior , Delivery of Health Care, Integrated/organization & administration , Diabetes Mellitus/therapy , Outcome and Process Assessment, Health Care/organization & administration , Patient Care Team/organization & administration , Primary Health Care/organization & administration , Quality of Health Care/organization & administration , Adult , Attitude of Health Personnel , Biomarkers/blood , Case Management/organization & administration , Diabetes Mellitus/blood , Female , Glycated Hemoglobin/metabolism , Guideline Adherence , Health Knowledge, Attitudes, Practice , Humans , Hypoglycemic Agents/therapeutic use , Male , Mexico , Middle Aged , National Health Programs/organization & administration , Organizational Objectives , Patient Education as Topic , Practice Guidelines as Topic , Program Evaluation , Referral and Consultation/organization & administration , Time Factors , Treatment Outcome , Young Adult
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