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1.
Phlebology ; 31(2): 111-7, 2016 Mar.
Article in English | MEDLINE | ID: mdl-25577573

ABSTRACT

OBJECTIVE: In this study involving a group of nurses employed in a number of different medical services with relatively well-defined working conditions, the presence and symptoms of chronic venous insufficiency were screened and their association with work burden and physical working conditions was explored. METHODS: Of the 294 actively employed nurses during the study period, 232 (79%) were recruited on the basis of their willingness for participation and fulfilment of the inclusion criteria. RESULTS: Among the study subjects, 62.9% had at least one symptom of chronic venous insufficiency, and 50.4% were found to have chronic venous insufficiency according to Clinical-Etiology-Anatomy-Pathophysiology classification criteria. A significant association was found between the diurnal ankle circumference difference in the left-right ankles and the mean duration of hospital stay. CONCLUSIONS: Our results have shown that the average duration of hospital stay, which is among the variables used to estimate the work burden of nurses, is associated with an increased frequency of the signs and symptoms of chronic venous insufficiency.


Subject(s)
Nurses , Occupational Exposure , Venous Insufficiency , Workload , Adult , Chronic Disease , Cross-Sectional Studies , Female , Humans , Prevalence , Venous Insufficiency/diagnosis , Venous Insufficiency/epidemiology , Venous Insufficiency/pathology , Venous Insufficiency/physiopathology
5.
Cardiovasc J Afr ; 23(10): e10-2, 2012 Nov 23.
Article in English | MEDLINE | ID: mdl-23192288

ABSTRACT

Surgical repair of postductal aortic coarctation associated with severe coronary artery disease is in most cases a difficult decision to make. As staged procedures are associated with a higher rate of morbidity and mortality, simultaneous operative management of both pathologies is desirable. We describe a case of a 51-year-old man who was referred to our department for surgical treatment of postductal aortic coarctation and concomitant coronary artery disease, which we managed with single-stage surgery through median sternotomy.


Subject(s)
Aortic Coarctation/surgery , Coronary Artery Bypass , Coronary Artery Disease/surgery , Sternotomy/methods , Angina, Unstable/etiology , Angina, Unstable/prevention & control , Aortic Coarctation/complications , Aortic Coarctation/diagnosis , Coronary Angiography , Coronary Artery Disease/complications , Coronary Artery Disease/diagnosis , Disease-Free Survival , Echocardiography , Humans , Hypertension/etiology , Hypertension/prevention & control , Male , Middle Aged
6.
J Laryngol Otol ; 122(8): 795-8, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18036275

ABSTRACT

BACKGROUND: The aim of this study was to investigate the differences between pre- and post-operative hearing thresholds, measured by high frequency audiometry, in patients undergoing open heart surgery. MATERIALS AND METHODS: Pre- and post-operative audiometric assessments were performed in 20 patients undergoing open heart surgery. Pure tone audiometry testing was performed at 500, 1000, 2000, 3000, 4000, 6000, 8000, 10 000, 12 000 and 14 000 Hz. We also evaluated: patients' clinical parameters (i.e. age, sex, diabetes mellitus, hypertension, hypercholesterolaemia, history of myocardial infarction, and whether undergoing coronary artery bypass surgery or valve surgery); various operative details (operative temperatures, cardiopulmonary bypass time and cross-clamp time); and post-operative clinical progress and its effect on hearing loss. RESULTS: Patients' pre- and post-operative pure tone audiometric results were significantly different at some frequencies (p < 0.05). In addition, there was a significant impact of hypertension, hypercholesterolaemia, history of myocardial infarction and cross-clamp time. CONCLUSIONS: This study shows that open heart surgery using cardiopulmonary bypass can lead to significant post-operative changes in hearing levels at some frequencies. Some additional patient parameters may influence this process. It seems possible that the risk of such hearing loss could be reduced; further studies may be able to define the significance of patients' concomitant disorders.


Subject(s)
Cardiopulmonary Bypass/adverse effects , Coronary Artery Bypass , Hearing Loss, Sensorineural/etiology , Heart Valve Prosthesis Implantation , Adult , Audiometry, Pure-Tone , Auditory Threshold , Female , Hearing Loss, Sensorineural/diagnosis , Humans , Hypercholesterolemia/complications , Hypertension/complications , Male , Middle Aged , Myocardial Infarction/complications , Postoperative Period , Prospective Studies , Risk Factors , Statistics, Nonparametric
7.
Transplant Proc ; 36(10): 2935-8, 2004 Dec.
Article in English | MEDLINE | ID: mdl-15686664

ABSTRACT

The purpose of this study was to investigate whether erythropoietin (EPO) has an effect on the expression of bcl-2 in rat cardiac myocytes following experimental isolated traumatic brain injury (TBI). Forty-eight Wistar-Albino female rats were randomly allocated into eight groups. Groups AC and BC were controls; groups AS and BS were sham-operated animals. Groups A1 and B1 underwent head trauma without treatment. Groups A2 and B2, head traumas plus EPO intraperitoneally (1000 IU/kg); groups A3 and B3, the vehicle groups, head traumas and intraperitoneal albumin (0.4 ml/rat). The method of weight drop was used to produce impact trauma at 24 hours after injury. Samples obtained from the left ventricle were assayed for lipid peroxidation and bcl-2 gene expression using real-time quantitative polymerase chain reactions. Lipid peroxidation in the heart tissue was determined by the concentration of thiobarbituric acid reactive substances (TBARs). The results showed that administration of EPO significantly reduced the increase in lipid peroxidation by-products after moderate or severe trauma. The bcl-2 expression was significantly higher in EPO (A2 and B2) compared to trauma groups (A1 and B1) suggesting a protective effect. These findings suggest that EPO may play an important role in the expression of bcl-2 and decrease in TBARs-the end product of lipid peroxidation in myocytes-after moderate or severe TBI.


Subject(s)
Brain Injuries/physiopathology , Erythropoietin/pharmacology , Genes, bcl-2/drug effects , Heart/physiology , Muscle Cells/physiology , Proto-Oncogene Proteins c-bcl-2/genetics , Animals , Disease Models, Animal , Female , Gene Expression Regulation/drug effects , Heart/drug effects , Lipid Peroxidation/drug effects , Muscle Cells/drug effects , Proto-Oncogene Proteins c-bcl-2/drug effects , Rats , Rats, Wistar , Thiobarbituric Acid Reactive Substances/metabolism
8.
J Heart Valve Dis ; 10(4): 548-9, 2001 Jul.
Article in English | MEDLINE | ID: mdl-11499606

ABSTRACT

Anticoagulation is mandatory in all mechanical valve replacements and, when well-managed, permits both embolism and valve thrombosis to be kept at low levels. Here, we report the case of a male patient who has survived 30 years without anticoagulation following aortic valve replacement with the Björk-Shiley prosthesis.


Subject(s)
Aortic Valve/transplantation , Heart Valve Prosthesis/adverse effects , Anticoagulants/therapeutic use , Humans , Male , Middle Aged , Survival , Thrombosis/prevention & control , Time Factors
9.
Tex Heart Inst J ; 27(3): 307-8, 2000.
Article in English | MEDLINE | ID: mdl-11093421

ABSTRACT

We report the benefits of using BioGlue surgical adhesive to repair an iatrogenic aortic rupture and dissection that resulted from cannulation of the ascending aorta during open-heart surgery.


Subject(s)
Aorta/injuries , Aortic Aneurysm/therapy , Aortic Dissection/therapy , Cardiac Surgical Procedures/adverse effects , Catheterization/adverse effects , Intraoperative Complications/therapy , Tissue Adhesives , Adult , Aortic Dissection/diagnosis , Aortic Dissection/etiology , Aortic Aneurysm/diagnosis , Aortic Aneurysm/etiology , Humans , Male
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