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Rev. argent. dermatol ; Rev. argent. dermatol;101(1): 111-120, mar. 2020. graf
Article in Spanish | LILACS | ID: biblio-1125812

ABSTRACT

Resumen El pénfigo foliáceo es una enfermedadversículo ampollar autoinmune poco frecuente,caracterizada histopatológicamente por acantólisis, inducida por la presencia de autoanticuerpos frente a la desmogleína 1. El desprendimiento se localiza en los estratos más superficiales de la epidermis produciendo ampollas frágiles y erosiones. Se clasifica en endémico y no endémico o esporádico. Dentro de este último podemos encontrar una variedad localizada y una generalizada. Presentamos el caso de un paciente, con diagnósticoy confirmación histopatológica de pénfigo foliáceo y realizamos una breve revisión de la literatura.


Summary Foliaceus pemphigus is an infrequent autoimmune blistering verse disease characterized histopathologically by acantholysis, induced by the presence of autoantibodies against desmoglein 1. The detachment is located in the most superficial layers of the epidermis produces fragile blisters and erosions. It is classified as endemic, and not endemic or sporadic. Within the latter we can find a localized and a generalized variety. Presents the case of a patient, diagnosis and histopathological confirmation of a paper and makes a brief review of the literature.


Subject(s)
Humans , Male , Adult , Pemphigus/diagnosis , Pemphigus/drug therapy , Biopsy/methods , Desmoglein 1/agonists
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