ABSTRACT
Two new phenolic compounds, epicaesalpin J and 7,10,11-trihydroxydracaenone, were isolated from the heartwood of Caesalpinia sappan L. Their structures were identified by spectroscopic analysis methods, such as 1D and 2D NMR, along with the high resolution mass spectral data. The NO inhibition activities of two new compounds and six known compounds were tested.
Subject(s)
Caesalpinia/chemistry , Phenols/chemistry , Wood/chemistry , Animals , Caesalpinia/metabolism , Inhibitory Concentration 50 , Metabolic Networks and Pathways , Microglia/drug effects , Molecular Structure , Nuclear Magnetic Resonance, Biomolecular , Phenols/metabolism , Phenols/pharmacologyABSTRACT
Two new compounds, a xanthonoid and a flavonoid C-glycoside, were isolated from the ethyl acetate extract of the dried herb of Comastoma pedunlulatum. The structures of the new compounds were elucidated, respectively, as 1,8-dihydroxy-3,5-dimethoxyxanthone 1-O-[2-(4'-hydroxy-3',5'-dimethoxy-E-cinnamoyl)]-ß-D-xylopyranosyl-(1-6)-ß-D-glucopyranoside (1) and 6â³-O-acetylisoorientin (2) on the basis of their spectroscopic and physicochemical properties.
