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1.
Lasers Med Sci ; 39(1): 106, 2024 Apr 18.
Article in English | MEDLINE | ID: mdl-38634947

ABSTRACT

The present study proposed a noninvasive, automated, in vivo assessment method based on optical coherence tomography (OCT) and deep learning techniques to qualitatively and quantitatively analyze the biological effects of 2-µm laser-induced skin damage at different irradiation doses. Different doses of 2-µm laser irradiation established a mouse skin damage model, after which the skin-damaged tissues were imaged non-invasively in vivo using OCT. The acquired images were preprocessed to construct the dataset required for deep learning. The deep learning models used were U-Net, DeepLabV3+, PSP-Net, and HR-Net, and the trained models were used to segment the damage images and further quantify the damage volume of mouse skin under different irradiation doses. The comparison of the qualitative and quantitative results of the four network models showed that HR-Net had the best performance, the highest agreement between the segmentation results and real values, and the smallest error in the quantitative assessment of the damage volume. Based on HR-Net to segment the damage image and quantify the damage volume, the irradiation doses 5.41, 9.55, 13.05, 20.85, 32.71, 52.92, 76.71, and 97.24 J/cm² corresponded to a damage volume of 4.58, 12.56, 16.74, 20.88, 24.52, 30.75, 34.13, and 37.32 mm³. The damage volume increased in a radiation dose-dependent manner.


Subject(s)
Deep Learning , Animals , Mice , Tomography, Optical Coherence , Disease Models, Animal , Lasers , Skin
3.
Sensors (Basel) ; 22(16)2022 Aug 21.
Article in English | MEDLINE | ID: mdl-36016050

ABSTRACT

At present, PPF-based point cloud recognition algorithms can perform better matching than competitors and be verified in the case of severe occlusion and stacking. However, including certain superfluous feature point pairs in the global model description would significantly lower the algorithm's efficiency. As a result, this paper delves into the Point Pair Feature (PPF) algorithm and proposes a 6D pose estimation method based on Keypoint Pair Feature (K-PPF) voting. The K-PPF algorithm is based on the PPF algorithm and proposes an improved algorithm for the sampling point part. The sample points are retrieved using a combination of curvature-adaptive and grid ISS, and the angle-adaptive judgment is performed on the sampling points to extract the keypoints, therefore improving the point pair feature difference and matching accuracy. To verify the effectiveness of the method, we analyze the experimental results in scenes with different occlusion and complexity levels under the evaluation metrics of ADD-S, Recall, Precision, and Overlap rate. The results show that the algorithm in this paper reduces redundant point pairs and improves recognition efficiency and robustness compared with PPF. Compared with FPFH, CSHOT, SHOT and SI algorithms, this paper improves the recall rate by more than 12.5%.


Subject(s)
Algorithms
4.
Entropy (Basel) ; 23(7)2021 Jul 03.
Article in English | MEDLINE | ID: mdl-34356399

ABSTRACT

In this paper, we present a derivation of the black hole area entropy with the relationship between entropy and information. The curved space of a black hole allows objects to be imaged in the same way as camera lenses. The maximal information that a black hole can gain is limited by both the Compton wavelength of the object and the diameter of the black hole. When an object falls into a black hole, its information disappears due to the no-hair theorem, and the entropy of the black hole increases correspondingly. The area entropy of a black hole can thus be obtained, which indicates that the Bekenstein-Hawking entropy is information entropy rather than thermodynamic entropy. The quantum corrections of black hole entropy are also obtained according to the limit of Compton wavelength of the captured particles, which makes the mass of a black hole naturally quantized. Our work provides an information-theoretic perspective for understanding the nature of black hole entropy.

5.
Phys Rev Lett ; 102(9): 098901; author reply 098902, 2009 Mar 06.
Article in English | MEDLINE | ID: mdl-19392569
6.
Phys Rev Lett ; 91(10): 109801, 2003 Sep 05.
Article in English | MEDLINE | ID: mdl-14525523
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