ABSTRACT
After one-month of oral treatment with traditional Chinese medicine decoction, without using other drugs, the lung inflammatory exudate, pulmonary fibrosis and quality of life of a 61-year-old female patient with corona virus disease 2019 (COVID-19) were significantly improved. No recurrence or deterioration of the patient's condition was found within seven weeks of treatment and follow-up, and no adverse events occurred, indicating that oral Chinese medicine decoction was able to improve the pulmonary inflammation and fibrosis in a patient recovering from COVID-19, but further research is still needed.
Subject(s)
Female , Humans , Middle Aged , Administration, Oral , COVID-19/virology , Drugs, Chinese Herbal/therapeutic use , Exudates and Transudates , Inflammation/etiology , Lung/pathology , Magnoliopsida , Medicine, Chinese Traditional , Phytotherapy , Pulmonary Fibrosis/etiology , SARS-CoV-2ABSTRACT
In the crystal structure of the title compound, C6H8N3O2 (+)·C6H2N3O7 (-)·H2O, N-Hâ¯O and O-Hâ¯O hydrogen bonds link the components into a two-dimensional network parallel to (010). In addition, there are pairs of weak inversion-related C-Hâ¯O hydrogen bonds within the two-dimensional network. The three nitro groups are twisted by 1.6â (3), 7.8â (3) and 12.1â (3)° from the ring plane in the anion, while in the cation, the nitro group makes a dihedral angle of 4.6â (2)° with the ring.
ABSTRACT
In the title compound, [ZnCl(2)(C(20)H(20)N(2))], the Zn(II) atom is four coordinated in a distorted tetra-hedral geometry by two N atoms of the Schiff base ligand and by two Cl atoms. Edge-to-face C-Hâ¯π inter-actions exist between mol-ecules, with a dihedral angle of 37.8â (1)° between the benzene ring planes and a shortest Hâ¯centroid distance of 3.62â (5)â Å.