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2.
Clin Infect Dis ; 14(2): 596-8, 1992 Feb.
Article in English | MEDLINE | ID: mdl-1554850

ABSTRACT

A 73-year-old man presented to our hospital 5 months after a porcine replacement of an aortic valve with persistent fevers, meningoencephalopathy, and progressive renal failure; evidence of systemic emboli was found subsequently. The results of an exhaustive evaluation were negative except for two of 23 blood cultures that were performed; each of these two cultures yielded one colony of Drechslera species (now known as Bipolaris) on one plate. Autopsy revealed a fungal vegetation (9.5 x 3.2 x 3.0 cm) in the ascending aorta that arose from suture material 1.0 cm distal to the aortic valve. Mycologic evaluation of the isolate revealed that it was Bipolaris spicifera.


Subject(s)
Bioprosthesis , Endarteritis/microbiology , Heart Valve Prosthesis , Mitosporic Fungi/isolation & purification , Mycoses/microbiology , Aged , Fungemia/microbiology , Humans , Male
4.
Am J Med ; 62(3): 404-8, 1977 Mar.
Article in English | MEDLINE | ID: mdl-842558

ABSTRACT

Peripheral blood cytopenia due to documented marrow necrosis is an unusual occurrence. This report describes a diabetic patient who presented with profound anemia and thrombocytopenia. Extensive bone marrow necrosis was demonstrated. He had a large renal cyst that contained hyphae later identified as Mucor species. It is postulated that the marrow necrosis was a direct or indirect result of Mucor infection. The phenomenon of bone marrow necrosis in reviewed.


Subject(s)
Mucormycosis/complications , Osteomyelitis/complications , Aged , Bone Marrow/pathology , Bone Marrow Cells , Cysts/microbiology , Humans , Kidney Diseases/microbiology , Male , Mucor/isolation & purification , Mucormycosis/diagnosis , Mucormycosis/microbiology , Mucormycosis/pathology , Necrosis , Osteomyelitis/diagnosis , Osteomyelitis/microbiology , Osteomyelitis/pathology , Thrombocytopenia/diagnosis
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