ABSTRACT
The authors describe seven patients in whom the administration of tiapride led to the disappearance of visual hallucinatory manifestations with the characteristics of "release hallucinations", the results being maintained throughout the period of treatment. The authors also discuss the mechanism and presumed site of action of the drug.
Subject(s)
Hallucinations/drug therapy , Tiapamil Hydrochloride/therapeutic use , AIDS-Related Opportunistic Infections/complications , Adult , Aged , Aged, 80 and over , Blindness/complications , Blindness/physiopathology , Brain Ischemia/complications , Cataract/complications , Cytomegalovirus Retinitis/complications , Female , Glaucoma/complications , Hallucinations/etiology , Hallucinations/physiopathology , Humans , Male , Middle Aged , Visual FieldsABSTRACT
The authors present 50 cases of "chronic constitutional tetany" observed in the E.M.T. laboratory of the Ospedali Riuniti di Finale e Pietra Ligure in the last 7 years. We consider various parameters regarding the sindrome (sex, age, season, headache etc.). We have studied all the cases from the electromyographic point of view, with adequate method, to reproduce, in the periods of latency, the characteristic E.M.G. and clinical features. The "tetanigenic threshold" appears abnormally low in these patients. In the today etiologic and physiopathologic doubt, the clinical and electromyographic criteria, assume a fundamental relevancy in the study of these patients, often defined as "functionalis".
Subject(s)
Electromyography , Tetany/diagnosis , Adolescent , Adult , Arrhythmias, Cardiac/complications , Asthma/complications , Calcium/blood , Child , Child, Preschool , Chronic Disease , Electroencephalography , Female , Humans , Magnesium/blood , Male , Middle Aged , Migraine Disorders/complications , Paresthesia/complications , Tetany/complications , Tetany/etiologySubject(s)
Amyotrophic Lateral Sclerosis/epidemiology , Adult , Age Factors , Aged , Amyotrophic Lateral Sclerosis/diagnosis , Female , Humans , Italy , Male , Middle Aged , Sex FactorsABSTRACT
The plasma lipid and lipoprotein pattern (total cholesterol, triglycerides and total lipid concentration; electrophoretic separation of the lipoproteins) and plasma protein profile (total protein concentration; electrophoretic separation of the plasma proteins) have been determined in a group of 60 chronic schizophrenic patients (47 men and 13 women, mean age 30,3 +/- 22 years). When compared to a control group matched for age and sex, the schizophrenic patients exhibited significantly lower cholesterol concentration and altered distribution pattern of the plasma lipid fractions. Similarly, the plasma a1,- a2,- and beta-globulin patterns are also altered in schizophrenic group. It is concluded that the altered plasma lipid and protein patterns may suggest that (auto)-immunologic and/or metabolic factors may be involved in the pathogenesis of schizophrenic disease.
