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Bioorg Med Chem Lett
; 23(22): 6188-91, 2013 Nov 15.
Article
in English
| MEDLINE
| ID: mdl-24070783
ABSTRACT
Acrylamide (S)-6, a potent and efficacious KCNQ2 (Kv7.2) opener, demonstrated significant activity in two models of neuropathic pain and in the formalin test, suggesting that KCNQ2 openers may be useful in the treatment of neuropathic pain including diabetic neuropathy.