Subject(s)
Arterial Occlusive Diseases/therapy , Blood Vessel Prosthesis , Femoral Artery , Leg/blood supply , Popliteal Artery , Saphenous Vein/transplantation , Sympathectomy , Aged , Arterial Occlusive Diseases/surgery , Femoral Artery/surgery , Humans , Lumbosacral Region , Male , Polytetrafluoroethylene , Popliteal Artery/surgeryABSTRACT
The glucuronyl transferase activity was measured with 1-naphthol as a substrate in nuclear and microsomal fractions of the human intestinal mucosa. The mucosa was obtained from different parts of the intestine. The rate of 1-naphthol glucuronidation ranged between 0.70 and 1.26 nmol/mg/min (nuclear fraction) and 0.21 and 0.54 nmol/mg/min (microsomal fraction). The average (+/- SEM) of the nuclear/microsomal ratios of the glucuronyl transferase was 2.48 +/- 0.19. The epoxide hydrolase activity towards styrene oxide was measured in the same subcellular fractions; it was undetectable in the nuclear fraction, whereas it was 0.46 +/- 0.04 nmol/mg/min (mean +/- SEM) in the microsomal fraction. The glucuronyl transferase activity was also measured in nuclear and microsomal fractions of the human liver. The activity (mean +/- SEM) was 1.14 +/- 0.21 nmol/mg/min (nuclei) and 5.00 +/- 0.80 (microsomes). The average of the nuclear to microsomal ratios (mean +/- SEM) was 0.32 +/- 0.03.
Subject(s)
Cell Nucleus/enzymology , Glucuronosyltransferase/analysis , Intestines/enzymology , Microsomes/enzymology , Naphthols/metabolism , Aged , Epoxide Hydrolases/analysis , Female , Humans , Male , Middle AgedSubject(s)
Gallstones/surgery , Aged , Common Bile Duct/surgery , Duodenum/surgery , Female , Hepatic Duct, Common/surgery , Humans , Jejunum/surgery , MaleSubject(s)
Fistula/therapy , Gastric Fistula/therapy , Parenteral Nutrition, Total , Parenteral Nutrition , Skin Diseases/therapy , Aged , Combined Modality Therapy , Female , Fistula/diagnosis , Gastric Fistula/diagnosis , Humans , Male , Middle Aged , Postoperative Complications , Skin Diseases/diagnosisSubject(s)
Duodenal Neoplasms , Lipoma , Duodenal Neoplasms/diagnosis , Duodenal Neoplasms/surgery , Humans , Lipoma/diagnosis , Lipoma/surgery , Male , Middle AgedSubject(s)
Adenocarcinoma, Papillary/surgery , Thyroid Neoplasms/surgery , Aged , Female , Humans , ThyroidectomyABSTRACT
Some comments are made on the association of chronic intestinal inflammatory conditions and articular manifestations on the basis of a case of Crohn's disease associated with ankylosing spondylitis and digitalic hippocratism. The clinical case is described and the literature on associations observed during Crohn's disease reviewed. Special attention is paid to associations involving ankylosing spondylitis, enteropathic synovitis and hypertrophic osteopathy, particularly as regards the presence of clubbed fingers.
