Subjective likelihood and the construal level of future events: A replication study of Wakslak, Trope, Liberman, and Alony (2006).

C. J. Wakslak, Y. Trope, N. Liberman, and R. Alony (2006) examined the effect of manipulating the likelihood of future events on level of construal (i.e., mental abstraction). Over 7 experiments, they consistently found that subjectively unlikely (vs. likely) future events were more abstractly (vs. concretely) construed. This well-cited, but understudied finding has had a major influence on the construal level theory (CLT) literature: Likelihood is considered to be 1 of 4 psychological distances assumed to influence mental abstraction in similar ways (Trope & Liberman, 2010). Contrary to the original empirical findings, we present 2 close replication attempts (N = 115 and N = 120; the original studies had N = 20 and N = 34) that failed to find the effect of likelihood on construal level. Bayesian analyses provided diagnostic support for the absence of an effect. In light of the failed replications, we present a meta-analytic summary of the accumulated evidence on the effect. It suggests a strong trend of declining effect sizes as a function of larger samples. These results call into question the previous conclusion that likelihood has a reliable influence on construal level. We discuss the implications of these findings for CLT and advise against treating likelihood as a psychological distance until further tests have established the relationship. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Departments involved during the first episode of acute heart failure and subsequent emergency department revisits and rehospitalisations: an outlook through the NOVICA cohort.

OBJECTIVES: We investigated the natural history of patients after a first episode of acute heart failure (FEAHF) requiring emergency department (ED) consultation, focusing on: the frequency of ED visits and hospitalisations, departments admitting patients during the first and subsequent hospitalisations, and factors associated with difficult disease control. METHODS AND RESULTS: We included consecutive patients diagnosed with FEAHF (either with or without previous heart failure diagnosis) in four EDs during 5 months in three different time periods (2009, 2011, 2014). Diagnosis was adjudicated by local principal investigators. The clinical characteristics of the index event were prospectively recorded, and all post-discharge ED visits and hospitalisations [related/unrelated to acute heart failure (AHF)], as well as departments involved in subsequent hospitalisations were retrospectively ascertained. 'Uncontrolled disease' during the first year after FEAHF was considered if patients were attended at ED (≥ 3 times) or hospitalised (≥ 2 times) for AHF or died. Overall, 505 patients with FEAHF were included and followed for a mean of 2.4 years. In-hospital mortality was 7.5%. Among 467 patients discharged alive, 288 died [median survival 3.9 years, 95% confidence interval (CI) 3.5-4.4], 421 (90%) revisited the ED (2342 ED visits; 42.4% requiring hospitalisation, 34.0% AHF-related) and 357 (77%) were hospitalised (1054 hospitalisations; 94.1% through ED, 51.4% AHF-related). AHF-related hospitalisations were mainly in internal medicine (28.0%), short-stay unit (26.3%), cardiology (20.8%), and geriatrics (14.1%). Only 47.4% of AHF-related hospitalisations were in the same department as the FEAHF, and internal medicine involvement significantly increased with subsequent hospitalisations (P = 0.01). Uncontrolled disease was observed in 31% of patients, which was independently related to age > 80 years [odds ratio (OR) 1.80, 95% CI 1.17-2.77], systolic blood pressure < 110 mmHg at ED arrival (OR 2.61, 95% CI 1.26-5.38) and anaemia (OR 2.39, 95% CI 1.51-3.78). CONCLUSION: In the present aged cohort of AHF patients from Barcelona, Spain, the natural history after FEAHF showed different patterns of hospital department involvement. Advanced age, low systolic blood pressure and anaemia were factors related to uncontrolled disease during the year after debut.

The mental representation of true and false intentions: a comparison of schema-consistent and schema-inconsistent tasks.

True and false intentions (i.e., lies and truths about one's future actions) is a relatively new research topic, despite the high societal value of being able to predict future criminal behavior (e.g., in the case of an alleged terrorist attack). The current study examined how true and false intentions are mentally represented - the knowledge of which can aid the development of new deception detection methods. Participants (N = 151) were asked either to form a true intention about a future task (i.e., retrieve objects from an office) or to form a false intention about the same task (i.e., prepare a cover story about retrieving objects from an office) to conceal their actual intention (i.e., leave a secret note in the office). The schema consistency of the task was manipulated by presenting participants with a list of office supplies (schema-consistent) or random objects (schema-inconsistent) to be retrieved from the office. The abstractness of mental construal was operationalized as the number of categories used by participants to organize the task-relevant objects into thematic groups. We predicted, based on construal level theory (CLT) and action identification theory, that participants would mentally represent true intentions more concretely (i.e., use a larger number of categories) than false intentions, particularly for schema-inconsistent (versus schema-consistent) future tasks. The results of the study lend no support for these predictions. Instead, a Bayesian analysis revealed strong evidence in favor of the null hypothesis. The findings indicate that predictions from CLT do not readily translate into deception contexts. The results are discussed in light of recent failed attempts to apply CLT to research on true and false intentions, and highlight the need for alternative approaches to the topic.

A propósito de dos casos de thelaziosis ocular humana / About two cases of human ocular thelaziosis

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Incremental diagnostic and prognostic value of the QRS-T angle, a 12-lead ECG marker quantifying heterogeneity of depolarization and repolarization, in patients with suspected non-ST-elevation myocardial infarction.

BACKGROUND: The value of the 12-lead ECG in the diagnosis of non-ST-elevation myocardial infarction (NSTEMI) is limited due to insufficient sensitivity and specificity of standard ECG criteria. The QRS-T angle reflects depolarization-repolarization heterogeneity and might assist in detecting patients with a NSTEMI (diagnosis) as well as predicting patients with an increased mortality risk (prognosis). METHODS: We prospectively enrolled 2705 consecutive patients with symptoms suggestive of NSTEMI. The QRS-T angle was automatically derived from the standard 10 s 12-lead ECG recorded at presentation to the ED. Patients were followed up for all-cause mortality for 2 years. RESULTS: NSTEMI was the final diagnosis in 15% (n = 412) of patients. QRS-T angles were significantly greater in patients with NSTEMI compared to those without (p < 0.001). The use of the QRS-T angle in addition to standard ECG criteria indicative of ischemia improved the diagnostic accuracy for NSTEMI as quantified by the area under the ROC curve from 0.68 to 0.72 (p < 0.001). An algorithm for the combined use of standard ECG criteria and the QRS-T angle improved the sensitivity of the ECG for NSTEMI from 45% to 78% and the specificity from 86% to 91% (p < 0.001 for both comparisons). The 2-year survival rates were 98%, 97% and 87% according to QRS-T angle tertiles (p < 0.001). CONCLUSION: In patients with suspected NSTEMI, the QRS-T angle derived from the standard 12-lead ECG provides incremental diagnostic accuracy on top of standard ECG criteria indicative of ischemia, and independently predicts all-cause mortality during 2 years of follow-up.

Drawing what lies ahead: False intentions are more abstractly depicted than true intentions.

The aim of this study was to examine how people mentally represent and depict true and false statements about claimed future actions-so-called true and false intentions. On the basis of construal level theory, which proposes that subjectively unlikely events are more abstractly represented than likely ones, we hypothesized that false intentions should be represented at a more abstract level than true intentions. Fifty-six hand drawings, produced by participants to describe mental images accompanying either true or false intentions, were rated on level of abstractness by a second set of participants (N = 117) blind to the veracity of the intentions. As predicted, drawings of false intentions were rated as more abstract than drawings of true intentions. This result advances the use of drawing-based deception detection techniques to the field of true and false intentions and highlights the potential for abstractness as a novel cue to deceit.

Diagnostic and prognostic value of QRS duration and QTc interval in patients with suspected myocardial infarction.

BACKGROUND: While prolongation of QRS duration and QTc interval during acute myocardial infarction (AMI) has been reported in animals, limited data is available for these readily available electrocardiography (ECG) markers in humans. METHODS: Diagnostic and prognostic value of QRS duration and QTc interval in patients with suspected AMI in a prospective diagnostic multicentre study were prospectively assessed. Digital 12-lead ECGs were recorded at presentation. QRS duration and QTc interval were automatically calculated in a blinded fashion. Final diagnosis was adjudicated by two independent cardiologists. The prognostic endpoint was all-cause mortality during 24 months of follow-up. RESULTS: Among 4042 patients, AMI was the final diagnosis in 19% of patients. Median QRS duration and median QTc interval were significantly greater in patients with AMI compared to those with other final diagnoses (98 ms [IQR 88-108] vs. 94 ms [IQR 86-102] and 436 ms [IQR 414-462] vs. 425 ms [IQR 407-445], p < 0.001 for both comparisons). The diagnostic value of both ECG signatures however was only modest (AUC 0.56 and 0.60). Cumulative mortality rates after 2 years were 15.9% vs. 5.6% in patients with a QRS > 120 ms compared to a QRS duration ≤ 120 ms (p < 0.001), and 11.4% vs. 4.3% in patients with a QTc > 440 ms compared to a QRS duration ≤ 440 ms (p < 0.001). After adjustment for age and important ECG and clinical parameters, the QTc interval but not QRS duration remained an independent predictor of mortality. CONCLUSIONS: Prolongation of QRS duration > 120 ms and QTc interval > 440 ms predict mortality in patients with suspected AMI, but do not add diagnostic value.

Do True and False Intentions Differ in Level of Abstraction? A Test of Construal Level Theory in Deception Contexts.

The aim was to examine how people mentally represent alleged future actions-their true and false intentions. In two experiments, participants were asked to either tell the truth (i.e., express true intentions) or lie (i.e., express false intentions) about performing future tasks. Drawing on Construal Level Theory, which proposes that psychologically distant events are more abstractly construed than proximal ones, it was predicted that liars would have more abstract mental representations of the future tasks than truth tellers, due to differences in hypotheticality (i.e., the likelihood of the future tasks occurring). Construal level was measured by a video segmentation task (Experiment 1, N = 125) and preference for abstract or concrete descriptions of tasks (Experiment 2, N = 59). Veracity had no effect on construal level. Speaking against our initial predictions, the data indicate that true and false intentions are construed at similar levels of abstraction. The results are discussed in the light of Construal Level Theory and the emerging psycho-legal research on true and false intentions.

Rapid cold hardening improves recovery of ion homeostasis and chill coma recovery time in the migratory locust, Locusta migratoria.

Chill tolerance of insects is defined as the ability to tolerate low temperature under circumstances not involving freezing of intracellular or extracellular fluids. For many insects chill tolerance is crucial for their ability to persist in cold environments and mounting evidence indicates that chill tolerance is associated with the ability to maintain ion and water homeostasis, thereby ensuring muscular function and preventing chill injury at low temperature. The present study describes the relationship between muscle and haemolymph ion homeostasis and time to regain posture following cold shock (CS, 2 h at -4°C) in the chill-susceptible locust Locusta migratoria. This relationship was examined in animals with and without a prior rapid cold-hardening treatment (RCH, 2 h at 0°C) to investigate the physiological underpinnings of RCH. CS elicited a doubling of haemolymph [K(+)] and this disturbance was greater in locusts pre-exposed to RCH. Recovery of ion homeostasis was, however, markedly faster in RCH-treated animals, which correlated well with whole-organism performance as hardened individuals regained posture faster than non-hardened individuals following CS. The present study indicates that loss and recovery of muscular function are associated with the resting membrane potential of excitable membranes as attested by the changes in the equilibrium potential for K(+) (EK) following CS. Both hardened and non-hardened animals regained movement once K(+) homeostasis had recovered to a fixed level (EK≈-41 mV). RCH is therefore not associated with altered sensitivity to ion disturbance but instead is correlated to a faster recovery of haemolymph [K(+)].

What experimental experience affects dogs' comprehension of human communicative actions?

Studies of dogs report that individuals reliably respond to the goal-directed communicative actions (e.g., pointing) of human experimenters. All of these studies use some version of a multi-trial approach, thereby allowing for the possibility of rapid learning within an experimental session. The experiments reported here ask whether dogs can respond correctly to a communicative action based on only a single presentation, thereby eliminating the possibility of learning within the experimental context. We tested 173 dogs. For each dog reaching our test criteria, we used a single presentation of six different goal-directed actions within a session, asking whether they correctly follow to a target goal (container with concealed food) a (1) distal hand point, (2) step toward one container, (3) hand point to one container followed by step toward the other, (4) step toward one container and point to the other, (5) distal foot point with the experimenter's hands free, and (6) distal foot point with the experimenter's hands occupied. Given only a single presentation, dogs selected the correct container when the experimenter hand pointed, foot pointed with hands occupied, or stepped closer to the target container, but failed on the other actions, despite using the same method. The fact that dogs correctly followed foot pointing with hands occupied, but not hands free, suggests that they are sensitive to environmental constraints, and use this information to infer rational, goal-directed action. We discuss these results in light of the role of experience in recognizing communicative gestures, as well as the significance of coding criteria for studies of canine competence.

Dual roles of glucose in the freeze-tolerant earthworm Dendrobaena octaedra: cryoprotection and fuel for metabolism.

Ectothermic animals inhabiting the subarctic and temperate regions have evolved strategies to deal with periods of continuous frost during winter. The earthworm Dendrobaena octaedra is freeze tolerant and accumulates large concentrations of glucose upon freezing. The present study investigates the roles of glucose accumulation for long-term freeze tolerance in worms kept frozen at -2 degrees C for 47 days. During this period, worms were sampled periodically for determination of survival and for measurements of glucose, glycogen, lactate, alanine and succinate. In addition we performed calorimetric measurements to assess metabolic rate of frozen and unfrozen worms. Long-term freezing was associated with a gradual depletion of glucose and worms that succumbed during this period were always characterised by low glucose and glycogen levels. The anaerobic waste products lactate and alanine increased slightly whereas succinate levels remained constant. However, it is argued that other waste products (particularly propionate) could be the primary end product of a continued anaerobic metabolism. Calorimetric measures of the metabolic rate of frozen worms were in accord with values calculated from the reduction in glucose assuming that most ( approximately 90%) glucose was metabolised anaerobically. Both estimates of metabolic rate demonstrated a 10-fold metabolic depression associated with freezing. Thus, in addition to the suspected role of glucose as cryoprotectant, the present study demonstrates that glucose accumulation is vital to ensure substrate for long-term anaerobic metabolism in frozen worms. On the basis of the estimated metabolite levels, we calculate that the combined effect of metabolic depression and large glucose stores enables a projected 3 months survival of freezing at -2 degrees C of the ;average' D. octaedra. Such conditions are very likely to occur in the northern distribution ranges of this stress-tolerant earthworm.