ABSTRACT
Las unidades médicas de corta estancia (UMCE) tienen un área de actuación preferente sobre una población en general anciana y pluripatológica cuyos diagnósticos más frecuentes suelen ser enfermedades de alta prevalencia, entre ellas las enfermedades cardiovasculares, conocidas o no. La enfermedad arterial periférica (EAP) es una manifestación de la arteriosclerosis en las extremidades inferiores. Un alto porcentaje de los pacientes no presentan sintomatología alguna o su diagnóstico resulta dificultoso. La detección de la EAP mediante el índice tobillo-brazo (ITB) es un método no invasivo y eficiente en la detección de la lesión vascular subclínica. Tiene una alta sensibilidad y especificidad para una estenosis (..) (AU)
The Medical Short Stay Units (UMCE) have an area of preferred on an elderly population and multipathological patients whose most common diagnoses for admission usually are high prevalence diseases. They coincide in a high presence of cardiovascular disease, whether known or not. Peripheral arterial disease (PAD) is one manifestation of arteriosclerosis that is defined by an obstruction of the arterial blood flow in the lower extremities. A high percentage of patients do not exhibit any symptoms and others have a difficult diagnosis. The detection of the PAD through the AnkleBrachial Index Measurement (ITB) is a non-invasive method, the scope of clinical, highly efficient in the detection of subclinical vascular injury. Objectives This technique offers a high sensitivity and specificity for stenosis (..) (AU)
Subject(s)
Humans , Peripheral Vascular Diseases/epidemiology , Arteriosclerosis/epidemiology , Cardiovascular Diseases/epidemiology , /statistics & numerical data , Smoking/adverse effects , Hypertension/epidemiologyABSTRACT
5-Fluorouracil-induced gastro-intestinal toxicity predominantly affects the upper and the lower gastro-intestinal tract. Although 5-fluorouracil (5-FU) can cause severe small-bowel toxicity, this has been reported only in 6 patients with colon carcinoma receiving 5-FU-based therapy. The presentation was extensive ulceration and inflammation of the small bowel with no involvement of the colon. We report another case of this toxicity, and discuss the diagnosis and mechanisms by which 5-FU can induce small-bowel toxicity.
Subject(s)
Antimetabolites, Antineoplastic/adverse effects , Colorectal Neoplasms/drug therapy , Fluorouracil/adverse effects , Ileitis/chemically induced , Aged , Female , HumansABSTRACT
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5-Fluorouracil-induced gastro-intestinal toxicity predominantly affects the upper and the lower gastro-intestinal tract. Although 5-fluorouracil (5-FU) can cause severe small-bowel toxicity, this has been reported only in 6 patients with colon carcinoma receiving 5-FU-based therapy. The presentation was extensive ulceration and inflammation of the small bowel with no involvement of the colon. We report another case of this toxicity, and discuss the diagnosis and mechanisms by which 5-FU can induce small-bowel toxicity