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Sci Total Environ ; 886: 163991, 2023 Aug 15.
Article in English | MEDLINE | ID: mdl-37169193

ABSTRACT

Endocrine disrupting chemicals (EDCs) can interfere with hormonal actions and have been associated with a higher incidence of metabolic disorders. They affect numerous physiological, biochemical, and endocrinal activities, including reproduction, metabolism, immunity, and behavior. The purpose of this review was to elucidate the association of EDCs in food with the gut microbiota and with metabolic disorders. EDC exposure induces changes that can lead to microbial dysbiosis. Products and by-products released by the microbial metabolism of EDCs can be taken up by the host. Changes in the composition of the microbiota and production of microbial metabolites may have a major impact on the host metabolism.


Subject(s)
Endocrine Disruptors , Gastrointestinal Microbiome , Metabolic Diseases , Humans , Endocrine Disruptors/toxicity , Dietary Exposure , Gastrointestinal Microbiome/physiology , Reproduction
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