Subject(s)
Antineoplastic Agents, Alkylating/adverse effects , Bendamustine Hydrochloride/adverse effects , Desensitization, Immunologic , Drug Hypersensitivity/therapy , Hypersensitivity, Delayed/therapy , Adult , Drug Hypersensitivity/diagnosis , Humans , Hypersensitivity, Delayed/diagnosis , Male , Skin TestsABSTRACT
Many types of seafood require cooking before ingestion and it has been demonstrated that this cooking process may affect the antigenicity and allergenicity of the food. We describe a case of anaphylaxis caused by selective sensitization to razor shell, a mollusc. In vivo and in vitro studies confirmed sensitization to boiled razor shell. Analysis of the nature of the allergen yielded results that were consistent with the findings of other authors and suggested that allergens involved in seafood allergy are commonly high molecular weight proteins that, in most cases, are heat stable.
Subject(s)
Anaphylaxis/etiology , Food Hypersensitivity/etiology , Shellfish/adverse effects , Adult , Animals , Cooking , Female , Food Hypersensitivity/diagnosis , Humans , Shellfish/analysis , Skin Tests/methodsABSTRACT
Few reports exist on allergic reactions to ranitidine. We present a case of bronchospastic reaction to ranitidine occurred during a drug challenge test. After administration of a therapeutic dose of ranitidine, the patient showed dyspnea, cough and bronchospasm in all the lung fields. Personal respiratory background was negative for respiratory disease and asthma. On reviewing the literature we found no reports of bronchospastic reaction to ranitidine. Quickness and the clinical characteristics of the adverse reaction suggest a pathogenic mechanism of immediate-type hypersensitivity.
Subject(s)
Anti-Ulcer Agents/adverse effects , Drug Hypersensitivity/etiology , Histamine H2 Antagonists/adverse effects , Ranitidine/adverse effects , Respiratory Hypersensitivity/etiology , Anti-Ulcer Agents/therapeutic use , Asthma , Gastroesophageal Reflux/drug therapy , Histamine H2 Antagonists/therapeutic use , Humans , Intradermal Tests , Male , Middle Aged , Ranitidine/therapeutic use , RhinitisSubject(s)
Analgesics, Opioid/adverse effects , Buprenorphine/adverse effects , Dermatitis, Allergic Contact/etiology , Administration, Cutaneous , Aged , Analgesics, Opioid/administration & dosage , Buprenorphine/administration & dosage , Dermatitis, Allergic Contact/diagnosis , Female , Humans , Patch TestsABSTRACT
La sensibilización al polen de olivo en la provincia de Zamora debería ser mínima debido a que el olivo, por sus características, no se adapta bien a las condiciones climáticas y a que se ha introducido recientemente en la mayoría de las zonas de la provincia como árbol ornamental. Hemos realizado un estudio retrospectivo descriptivo que ha observado una sensibilización llamativa al polen del olivo, que aumenta en las zonas urbanas
Sensitization to olive pollen should not be important in Zamora city and province because, due to its characteristics, this tree doesn´t adapt to weather conditions in the city and because it has been recently introduced in most of the provinces areas as an ornamental tree. We have performed a retrospective descriptive study observing a significant level of sensitization to olive pollen, which is growing in urban zones
Subject(s)
Male , Female , Humans , Pollen/adverse effects , Pollen/immunology , Environmental Pollution/adverse effects , Olea/adverse effects , Olea/immunology , Allergens/adverse effects , Desensitization, Immunologic/methods , Rhinitis/epidemiology , Asthma/epidemiology , Skin Tests/methods , Spain/epidemiology , Epidemiology, Descriptive , Retrospective Studies , Air Pollution/adverse effects , Allergens/analysis , Asthma/immunology , Rhinitis/immunology , Skin Tests/trends , Skin TestsABSTRACT
BACKGROUND: There are few references of allergic reaction to beans in childhood. We report the case of a seven years old boy who suffered from angioedema associated to inhalation of vapours from cooked white bean. METHODS: skin prick tests (SPT) were performed by prick-by-prick with cooked white bean and legumes. It was also determined total IgE and specific IgE antibodies to bean and legumes with the use of the CAP enzymo-immunoassay. Subsequently, a oral challenge test was carried out with white bean. RESULTS: The prick-by-prick with white bean was positive in our case, and negative in ten controls patients. Specific IgE in patient serum, assayed by CAP was positive for white bean and green bean. The patient developed angioedema after ingestion cooked white bean. CONCLUSION: we demonstrated a type I hypersensitivity to white bean in a seven years old child by SPT, specific IgE antibodies and challenge test.
Subject(s)
Angioedema/etiology , Antigens, Plant/adverse effects , Food Hypersensitivity/etiology , Gases/adverse effects , Hypersensitivity, Immediate/etiology , Phaseolus/adverse effects , Acute Disease , Antibody Specificity , Child , Cooking , Environmental Exposure , Food Hypersensitivity/immunology , Humans , Hypersensitivity, Immediate/immunology , Immunoglobulin E/blood , Immunoglobulin E/immunology , Inhalation , Male , Plant Extracts/adverse effects , Skin TestsABSTRACT
Background: There are few references of allergic reaction to beans in childhood. We report the case of a seven years old boy who suffered from angioedema associated to inhalation of vapours from cooked white bean. Methods: skin prick tests (SPT) were performed by prick-by-prick with cooked white bean and legumes. It was also determined total IgE and specific IgE antibodies to bean and legumes with the use of the CAP enzymo-immunoassay. Subsequently, a oral challenge test was carried out with white bean. Results: The prick-by-prick with white bean was positive in our case, and negative in ten controls patients. Specific IgE in patient serum, assayed by CAP was positive for white bean and green bean. The patient developed angioedema after ingestion cooked white bean. Conclusion: we demonstrated a type I hypersensitivity to white bean in a seven years old child by SPT, specific IgE antibodies and challenge test
Antecedentes: Hay pocas referencias de reacciones alérgicas a alubias en la infancia. Presentamos el caso de un niño de siete años que refiere angioedema asociado a la inhalación de vapores de alubias blancas cocidas. Métodos: Se realizaron pruebas cutáneas por prick-by-prick con alubia blanca y legumbres. También se determinó IgE total e IgE específica a legumbres. Posteriormente, se realizó provocación oral con alubia blanca. Resultados: El prick-by-prick con alubia blanca fue positivo en el paciente y negativo en 10 controles. La determinación de IgE específica fue positiva para alubia blanca y alubia verde. El paciente desarrolló angioedema tras provocación oral con alubia blanca. Conclusión: Hemos demostrado una reacción de hipersensibilidad tipo I a alubia blanca en un niño de 7 años por pruebas cutáneas, IgE específica y provocación oral
