Subject(s)
Respiratory Distress Syndrome, Newborn , Respiratory Distress Syndrome , Dyspnea , Humans , Infant , Infant, Newborn , Respiratory Distress Syndrome/diagnosis , Respiratory Distress Syndrome/therapy , Respiratory Distress Syndrome, Newborn/diagnosis , Respiratory Distress Syndrome, Newborn/therapy , ResuscitationSubject(s)
Genetic Predisposition to Disease , Neurofibromatosis 1/diagnosis , Xanthogranuloma, Juvenile/diagnosis , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Male , Neurofibromatosis 1/complications , Neurofibromatosis 1/genetics , Neurofibromatosis 1/pathology , Risk Factors , Xanthogranuloma, Juvenile/complications , Xanthogranuloma, Juvenile/genetics , Xanthogranuloma, Juvenile/pathologySubject(s)
Facial Neoplasms/diagnosis , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis , Skin Neoplasms/diagnosis , Child, Preschool , Diagnosis, Differential , Facial Neoplasms/pathology , Female , Forehead/pathology , Humans , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology , Skin Neoplasms/pathologySubject(s)
Pain , Scrotum , Acute Disease , Child , Family , Humans , Male , Pain/diagnosis , Pain/etiology , Scrotum/diagnostic imagingABSTRACT
OBJECTIVES: Injuries are one of the most common causes of pediatric emergency department (ED) visit. The aim of this study was to investigate the relationship between the intensity of pain at the ED visit of children presenting with an extremity injury and the risk of fracture. METHODS: We conducted a retrospective study, considering all patients presenting to the ED of a children's hospital in Italy, with an accidental extremity injury, between May and December 2015. We selected all children aged 8 to 17 years who underwent an x-ray. Children with major, multiple, or nonextremity injuries were excluded. Age, sex, spontaneous and palpation pain, local swelling, time between injury, and medical evaluation were recorded. Sensibility and specificity of spontaneous and palpation pain in detecting a fracture were calculated. RESULTS: We reviewed 994 medical records; of these, 344 (34.6%) reported a fracture. Children's median age was 12 years (interquartile range [IQR], 10-14). Median spontaneous pain at the ED visit was not significantly different between children with and without a fracture: 4.0 (1.0-6.0) and 5 (1.0-6.0), respectively (P = 0.129). Children with mild palpation pain and children without an increase of pain of at least 2 points between spontaneous and palpation pain were fractured in 3.2% and 0.97% of cases, respectively. CONCLUSIONS: In this series, pain intensity in children with a minor extremity injury was not a good marker of fracture. Nevertheless, children with mild palpation pain or with a mild increase of pain between spontaneous and palpation pain had a low risk of fracture.
Subject(s)
Fractures, Bone , Pain Measurement , Pain , Wounds and Injuries , Adolescent , Child , Emergency Service, Hospital , Extremities , Fractures, Bone/diagnostic imaging , Humans , Italy , Retrospective StudiesABSTRACT
In June 2013, the European Medicine Agency recommended limiting codeine use in paediatric patients, creating a void in managing moderate pain. We reviewed the literature published in English (1985-June 2017) on the pharmacokinetic, pharmacodynamic and safety profile of ketorolac, a possible substitute for codeine and opioids, for treating moderate-to-severe pain. We found that gastrointestinal side effects were mainly reported with prolonged use, significant bleeding was reported in adenotonsillectomy, and adverse renal effects appeared to be limited to patients with specific coexisting risk factors. CONCLUSION: The short-term use of ketorolac appears to be safe for children in many situations.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Ketorolac/pharmacology , Pain/drug therapy , Age Factors , Child , Child, Preschool , Humans , InfantABSTRACT
: A 15-year-old girl was admitted with acute crampy abdominal pain and repeated vomiting over the preceding 2â hours; no fever, diarrhoea or abdominal trauma was reported. She had started oestrogen-progestin contraception 3â months ago. She had sought medical advice twice in the previous weeks for self-limiting episodes of right hand swelling, without urticaria. On examination, she was unwell and in pain, with severe tenderness in the right lower quadrant, without guarding or rebound tenderness. Bowel sounds were diminished. Blood tests were unremarkable. Two hours after admission, an abdominal ultrasound scanning showed an impressive wall thickening (>1â cm) of the terminal ileum, caecum and ascending colon (figure 1). Abundant free intraperitoneal fluids in the pelvis and in the hepatorenal recess were present.edpract;103/1/22/EDPRACT2016311823F1F1EDPRACT2016311823F1Figure 1Marked caecal wall thickening evidenced at the ultrasound scanning. QUESTIONS: Which of the following is the most likely diagnosis in this patient? Ileocolic intussusceptionGastrointestinal manifestation of Henoch-Schönlein purpuraAbdominal attack of hereditary angioedema (HAE)Acute pancreatitisWhich of the following blood tests may help to confirm the diagnosis? Erythrocyte sedimentation rateC4Serum amylase: 36â IU/LC1-inhibitorHow should this patient be evaluated and treated?Answers are on page âªâªâª.
Subject(s)
Abdominal Pain/diagnosis , Abdominal Pain/drug therapy , Angioedema/diagnosis , Angioedema/drug therapy , Complement C1 Inhibitor Protein/therapeutic use , Inflammatory Bowel Diseases/diagnostic imaging , Inflammatory Bowel Diseases/drug therapy , Adolescent , Female , Humans , Treatment Outcome , UltrasonographyABSTRACT
AIM: Early-revisits are frequent in the paediatric emergency department (ED) setting, but few data are available about early-revisited patients. The aim of this study was to investigate the hospitalisation rate of a population of early-revisited patients and to detect if an early-revisited patient was at risk of a more severe disease. METHODS: Between June 2014 and January 2015, we conducted a retrospective cohort study, considering all patients presented to the ED of a tertiary level children's hospital in Italy. We selected all patients who were revisited within 72 h from the initial visit (study cohort), while all other patients accessed in the same period were considered the control cohort. The two cohorts were compared for age, gender, triage category, hospitalisation rate, diagnosis at admission and hospital length of stay. RESULTS: In the study period, we reviewed 10 750 visits, of which 430 (4%) were unplanned revisits for the same chief complaint within 72 h from the initial visit. Hospitalisation rate of early-revisited patients was significantly higher compared to control patients (8.4 vs. 2.9%). Hospitalisation rate increases in parallel with the number of revisits, but in many cases, it was not directly related to a worst triage category, neither to a longer hospital length of stay. CONCLUSION: Early revisited patients in the ED had a significantly higher risk of hospitalisation, but this risk was only partially related to their clinical conditions.
Subject(s)
Emergency Service, Hospital , Hospitalization , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Italy , Male , Retrospective Studies , Risk Assessment , Tertiary Care Centers , Time FactorsABSTRACT
Pain is common in children presenting to emergency departments with episodic illnesses, acute injuries, and exacerbation of chronic disorders. We review recognition and assessment of pain in infants and children and discuss the manifestations of pain in children with chronic illness, recurrent pain syndromes, and cognitive impairment, including the difficulties of pain management in these patients. Non-pharmacological interventions, as adjuncts to pharmacological management for acute anxiety and pain, are described by age and development. We discuss the pharmacological management of acute pain and anxiety, reviewing invasive and non-invasive routes of administration, pharmacology, and adverse effects.
Subject(s)
Acute Pain/therapy , Analgesics, Opioid/therapeutic use , Anesthetics, Local/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Anxiety/therapy , Emergency Service, Hospital , Pain Management/methods , Stress, Psychological/therapy , Acute Pain/psychology , Anxiety/psychology , Child , Emergency Medicine , Humans , Pediatrics , Stress, Psychological/psychologySubject(s)
Arteriovenous Malformations/complications , Calculi/etiology , Hand/blood supply , Arteriovenous Malformations/diagnostic imaging , Calcinosis/diagnostic imaging , Calcinosis/etiology , Calculi/diagnostic imaging , Child , Female , Hand Deformities, Congenital/complications , Humans , RadiographyABSTRACT
A pseudotumoral presentation of acute hemicerebellitis is rare in pediatric age. The authors report a new single case study of a 7-year-old child with pseudotumoral unilateral cerebellitis mimicking an intracranial tumor, which clinically presented itself with signs of intracranial hypertension and mild contralateral hemiparesis, completely recovered after anti-inflammatory therapy. Brain magnetic resonance imaging (MRI) was essential for the differential diagnosis between inflammatory and neoplastic processes. The literature highlighting specific clues about pseudotumoral hemicerebellitis as a distinct clinical and radiological entity is reviewed.
Subject(s)
Brain/pathology , Cerebellar Diseases/diagnosis , Cerebellar Diseases/pathology , Encephalitis/diagnosis , Encephalitis/pathology , Cerebellar Diseases/drug therapy , Child , Diagnosis, Differential , Encephalitis/drug therapy , Humans , Magnetic Resonance Imaging , MaleABSTRACT
UNLABELLED: The European Medicine Agency recommendations limiting codeine use in children have created a void in managing moderate pain. We review the evidence on the pharmacokinetic, pharmacodynamic and safety profile of tramadol, a possible substitute for codeine. CONCLUSION: Tramadol appears to be safe in both paediatric inpatients and outpatients. It may be appropriate to limit the current use of tramadol to monitored settings in children with risk factors for respiratory depression, subject to further safety evidence.