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2.
Urology ; 103: e7-e8, 2017 May.
Article in English | MEDLINE | ID: mdl-28216451

ABSTRACT

We report the first documented case of malignant melanoma obstructing ureters of both moieties of a duplex kidney and contralateral single moiety ureter in a 51-year-old male. The patient presented with fever, coryzal symptoms, and liver function test derangement several years after 2 superficial spreading melanomas were excised with clear margins. Ultrasonography demonstrated hydronephroureter in both moieties of a complete right-sided duplex kidney. Retrograde pyelograms showed bilateral hydronephroureter and filling defects in all 3 ureters. Biopsied tumor cells were positive for S100, Melan A, and HMB45. Cutaneous melanoma metastasizing to ureters is a rare phenomenon and can present a diagnostic challenge to clinicians if clinically silent.

3.
BJU Int ; 118 Suppl 3: 43-48, 2016 Oct.
Article in English | MEDLINE | ID: mdl-27659257

ABSTRACT

OBJECTIVES: To analyse the Australian experience of high-volume Fellowship-trained Laparoscopic Radical Prostatectomy (LRP) surgeons. MATERIALS AND METHODS: 2943 LRP cases were performed by nine Australian surgeons. The inclusion criteria were a prospectively collected database with a minimum of 100 consecutive LRP cases. The surgeons' LRP experience commenced at various times from July 2003 to September 2009. Data were analysed for demographic, peri-operative, oncological and functional outcomes. RESULTS: The mean age of patients were 61.5 years and mean preoperative PSA 7.4 ng/ml. Mean operating time was 168 minutes with conversion to open surgery in 0.5% and a blood transfusion rate of 1.1%. Overall mean length of stay was 2.5 days. 73.6% of pathological specimens were pT2 and 86.3% had Gleason Score >7. Overall positive surgical margins (PSM) occurred in 15.9% with pT2 PSM 9.8%, pT3a PSM 30.8% and pT3b PSM 39.2%. Mean urinary continence at 12 months was 91.4% (data available from five surgeons). Mean 12 months potency after bilateral nerve spare was 47.2% (data available from four surgeons). Biochemical recurrence occurred in 10.6% (mean follow up 17 months). CONCLUSION: The Australian experience of Fellowship trained surgeons performing LRP demonstrates favourable peri-operative, oncological and functional outcomes in comparison to published data for open, laparoscopic and robotic assisted radical prostatectomy. In our Australian centres, LRP remains an acceptable minimally invasive surgical treatment for prostate cancer despite the increasing use of robotic assisted surgery.


Subject(s)
Laparoscopy , Prostatectomy , Prostatic Neoplasms/mortality , Prostatic Neoplasms/surgery , Adult , Aged , Aged, 80 and over , Australia/epidemiology , Blood Transfusion/statistics & numerical data , Fellowships and Scholarships , Humans , Laparoscopy/methods , Laparoscopy/mortality , Length of Stay/statistics & numerical data , Male , Middle Aged , Neoplasm Grading , Operative Time , Prospective Studies , Prostate/pathology , Prostatectomy/methods , Prostatectomy/mortality , Prostatic Neoplasms/pathology , Robotic Surgical Procedures , Seminal Vesicles/pathology , Surgeons/education , Treatment Outcome
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