Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Chem Commun (Camb) ; 57(83): 10867-10870, 2021 Oct 19.
Article in English | MEDLINE | ID: mdl-34665184

ABSTRACT

A new CEST-MRI contrast agent, 2-HYNIC, capable of sensing aromatic aldehydes is reported. Pyridoxal 5'-phosphate, a key Vitamin B6 metabolite necessary for >140 biotransformations was mapped by CEST-MRI in vitro and in vivo in lung cancer. 2-HYNIC provided access to this key biomarker associated with a variety of human diseases.


Subject(s)
Contrast Media/chemistry , Hydrazines/chemistry , Niacin/analogs & derivatives , Vitamin B 6/metabolism , Cell Line, Tumor , Humans , Magnetic Resonance Imaging/methods , Neoplasms/diagnostic imaging , Neoplasms/metabolism , Vitamin B 6/chemistry
SELECTION OF CITATIONS
SEARCH DETAIL
...