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Med Clin (Barc) ; 135(13): 581-5, 2010 Nov 06.
Article in Spanish | MEDLINE | ID: mdl-20557907

ABSTRACT

UNLABELLED: FUNDAMENTAL AND OBJECTIVE: To present the first experiences with a series of consecutive cases of patients with non-small cell lung cancer (NSCLC) treated with radiofrequency ablation (RFA), considering its clinical applicability, effectiveness and safety. PATIENTS AND METHODS: Descriptive study performed from June 2003 to March 2009, with a series of consecutive cases of patients with NSCLC treated with RFA, selected according to well-defined inclusion criteria, in different stages of the disease. The variables studied were local recurrence, complications, staging, demographic and procedure-related variables. Local control was assessed in posterior controls according to CT morphology criteria and/or lesion enhancement after intravenous contrast. Survival curves were estimated. Statistical analysis was performed with SPSS version 15.0 application. RESULTS: We studied 15 patients (46-88 years), diagnosed with NSCLC in different stages, in a total of 22 sessions. After 1 year of follow up, 75% of lesions showed no local recurrence (15). The progression-free survival and disease-free survival in localized stage at one year were 81,3% and 75% respectively. In 8 of 22 sessions there were post-procedure complications (36.36%). Of all complications (14), 28.5% were pneumothorax, 21.4% alveolar hemorrhage and 7.1% pulmonary infarction. CONCLUSION: ARF is clinically useful in the treatment of patients with inoperable NSCLC, considering the high percentage of local control and few major complications, being thus a plausible, effective and safe therapeutic alternative.


Subject(s)
Carcinoma, Non-Small-Cell Lung/surgery , Catheter Ablation , Lung Neoplasms/surgery , Radiography, Interventional , Tomography, X-Ray Computed , Aged , Aged, 80 and over , Carcinoma, Non-Small-Cell Lung/diagnostic imaging , Female , Humans , Kaplan-Meier Estimate , Lung Neoplasms/diagnostic imaging , Male , Middle Aged , Postoperative Complications/epidemiology , Retrospective Studies , Survival Rate , Treatment Outcome
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