Assessment on bioactive role of Moringa oleifera leaves as anthelmintic agent and improved growth performance in goats.

The aim of this study was to evaluate the bioactive effect of Moringa oleifera leaves hydroalcoholic extract as a dietary feed additive on helminths load and growth performances of goats. Initially, the availability of bioactive compounds in M. oleifera hydroalcoholic extract was analysed using gas chromatography-mass spectrometry (GC-MS), which showed the presence of heneicosane (35.69%), 1,2-benzenedicarboxylic acid (22.89%), heptacosane (18.26%), pentatriacontane (4.77%), and hexadecanoic acid ethyl ester (3%) as predominant compounds in the leaves extract. The anthelmintic effect of M. oleifera extract (0 and 60 mL of extract animal-1) was evaluated against disparate nematodes using standard methodology. M. oleifera leaves extract exhibited significant (P = 0.002) anthelmintic activities against Trichuris sp. and Ostertagia sp. with reduced counts of eggs. A completely randomized experiment of 3 treatments comprised of 10 goats in each treatment was designed for the growth performance study. Treatments used in the present experiment were as follows: treatment 1 (T1), 0 mL of extract animal-1; treatment 2 (T2), 30 mL of extract animal-1; and treatment 3 (T3), 60 mL of extract animal-1. Growth performance parameters (body weight, daily weight gain, and feed intake values) of goats fed varied concentrations of M. oleifera extract were estimated as per standard protocols. The T2 and T3 groups' goats offered significant (P < 0.05) increment in body weight. Daily weight gain of the T2 and T3 groups' goats was also increased. Group T3 exhibited maximum feed intake value of 588, 678, 652, and 678 g d-1 at 0, 30, 45, and 60 days, respectively. Feed conversion efficiency was increased for T2 and T3 groups' goats versus T1. Findings of this study concluded that M. oleifera hydroalcoholic extract can be used not only as an effective anthelmintic agent against disparate nematodes but also as a prominent feed additive to improve growth performances of goats.

Effect of Slow-Release Pellets of Selenium and Iodine on Performance and Some Blood Metabolites of Pregnant Moghani Ewes and Their Lambs.

The need for minerals during pregnancy in mammals increases by progress of gestation due to embryo development. Therefore, the supply of trace minerals for pregnant ewes in late pregnancy may be of vital importance. The present study was carried out to evaluate the effect of selenium and iodine release slowly on the performance and some blood parameters of pregnant ewes and their lambs. Experiments were performed on 40 pregnant ewes from 3 to 4 years old in the last month of pregnancy with a weighing average of 52 ± 5 kg and a factorial experiment (2 × 2) in a completely randomized design with 4 treatments and 10 replicates used for 120 days (30 days before and 90 days after parturition of ewes). Experimental treatments were containing the following: (1) control, (2) ewe receiving bolus containing iodine, (3) ewe receiving bolus containing iodine and selenium, and (4) ewe receiving bolus containing selenium. One month before the expected birth date, the pellets will be fed to each of the livestock by bolus gun. During the test period, ewes will not receive any other mineral supplements and will be kept in a group in a herd. Ewes were blood sampled at 10 days prepartum and 30 and 60 days postpartum. The results showed that body weight on birth and weaning of lambs and average daily gain of lambs were highest in bloused animals that were related to the slow-release selenium tablet lambs (P < 0.05). Lambs born to mothers receiving 0.3 mg day-1 of selenium per day had a keratin phosphokinase concentration of T4 concentration and T4 to T3 lower than that of zero selenium (P < 0.05). Daily gain, glutathione peroxidase activity, and T4 concentration at iodine 0.4 mg day-1 were significantly higher than iodine level (P < 0.05). The adding of slow- release pellets of iodine and selenium improved the immune system.