1.
Acta Biomed Ateneo Parmense
; 60(5-6): 245-8, 1989.
Article
in Italian
| MEDLINE
| ID: mdl-2535199
ABSTRACT
The case of a patient who developed megaloblastic anemia caused by folate deficiency during treatment with primidone is reported. The serum level of folic acid was significantly low. Two causes able to produce folate deficiency have been discovered: chronic assumption of primidone, and low dietary intake of folic acid. The anemia was completely reversed by oral supplementation of folic acid. It has already been recognized that additional nutritional deficiency is required to precipitate a frank megaloblastic anemia during therapy with antiepileptic drugs.
Subject(s)
Anemia, Megaloblastic/chemically induced , Primidone/adverse effects , Administration, Oral , Anemia, Megaloblastic/blood , Anemia, Megaloblastic/drug therapy , Folic Acid/administration & dosage , Folic Acid/blood , Humans , Male , Middle Aged
2.
Boll Chim Farm
; 106(7): 463-6, 1967 Jul.
Article
in Italian
| MEDLINE
| ID: mdl-5599311