[Aspects of the etiological diagnosis of extrapulmonary tuberculous infections]. / Aspecte privind diagnosticul etiologic al infectiilor tuberculoase extrapulmonare.

An analysis is made of criteria used for making an etiologic diagnosis of extra-pulmonary tuberculosis over a period of 15 years, and a general correlation is noted between the figures for morbidity and those of bacteriologic confirmations. In the group of patients which has been investigated the diagnosis could be ascertained from urine samples in 44% of the cases, from lymph-nodes and nodules in 15% from pleural fluids in 14%, from purulent collections in 13%, and from the cerebrospinal fluid in 8% of the cases. Human type mycobacteria was evidenced in 90% of the cases. Bovine type of mycobacteria was found in 5% of the cases, with a higher frequency in the cerebrospinal fluid (14%) and in lymph-nodes (11%). In 79% of the cases the antibiogram has evidenced the sensitivity of the isolated strains. Resistance of the strains was noted in 10% of the cases. The strains isolated from lymph-nodes and nodules were resistant in a higher proportion (11%), and those from the pleural fluid in 15%.

[Bacteriological and epidemiological observations on atypical mycobacteria isolated at the laboratory of the Cluj-Napoca Tuberculosis Hospital]. / Observatii bacteriologice si epidemiologice legate de microbacteriile atipice izolate în laboratorul Spitulului de tuberculoza Cluj-Napoca.

Excluding cases of clinically manifest mycobacteriosis atypical mycobacteria can be detected in the excreta of healthy subjects, of tuberculous patients, or of other patients suffering from other diseases, without any major clinical implication. In certain environment conditions however epidemiologic manifestations may be induced by these organisms, of the hospitalism type. Atypical strains of the mycobacteria isolated over a period of 10 years represent 3.17% of all isolated strains. The highest percentage according to the Runyon groups were found in the IV-th group (43%), followed by the II-nd group (with 42%), and the III-rd group (with 11%). Diffusion of mycobacteria from the II-nd and the IV-th Runyon groups has determined hospitalism phenomena that developed in two distinct epidemic outbreaks determined by different factors.