ABSTRACT
OBJECTIVE: The aim of this study was to evaluate the prevalence and risk factors related to metabolic dysfunction-associated steatotic liver disease in inflammatory bowel disease patients. METHODS: This is a cross-sectional study conducted on adults with inflammatory bowel disease from 2019 to 2021. Metabolic dysfunction-associated steatotic liver disease encompasses patients with steatosis and at least one cardiometabolic risk factor. Patients with alcohol consumption ≥20 g/day, chronic liver diseases, or methotrexate use were excluded. RESULTS: Almost 140 patients were included: 67.1% were female, with a mean age of 49.7±13.7 years, and 63.6% had Crohn's disease. The mean duration of inflammatory bowel disease was 9.7±7.9 years. Metabolic dysfunction-associated steatotic liver disease was observed in 44.3% and advanced liver fibrosis was excluded in 63.5% by Fibrosis-4. Patients with metabolic dysfunction-associated steatotic liver disease were older (p = 0.003) and had a higher number of metabolic syndrome components (2.9±1.1 versus 1.6±1.0; p<0.001), greater abdominal circumference (p<0.001), and body mass index (p<0.001). The only factor related to inflammatory bowel disease associated with metabolic dysfunction-associated steatotic liver disease was disease duration (11.6±9.5 versus 8.3±6.2; p = 0.017). A higher number of metabolic syndrome components and obesity increase by 2.2 times and an altered waist circumference by 2.6 times the occurrence of metabolic dysfunction-associated steatotic liver disease. CONCLUSION: A high prevalence of metabolic dysfunction-associated steatotic liver disease was observed in patients with inflammatory bowel disease, with the main risk factors being associated with metabolic syndrome predicting it, but not with inflammatory bowel disease features and/or its treatment.
Subject(s)
Inflammatory Bowel Diseases , Metabolic Syndrome , Humans , Female , Male , Middle Aged , Cross-Sectional Studies , Prevalence , Adult , Risk Factors , Metabolic Syndrome/epidemiology , Metabolic Syndrome/complications , Inflammatory Bowel Diseases/complications , Inflammatory Bowel Diseases/epidemiology , Tertiary Care Centers , Brazil/epidemiology , Fatty Liver/epidemiology , Fatty Liver/complications , Body Mass Index , Non-alcoholic Fatty Liver Disease/epidemiology , Non-alcoholic Fatty Liver Disease/complicationsABSTRACT
The authors report the case of a 55-year-old female, hypertensive, smoker patient presenting with dysphonia, dysphagia and persistent dry cough. Laryngoscopy diagnosed left vocal cord paralysis. Computed tomography demonstrated saccular aneurysm of the inferior wall of the aortic arch, stretching the left recurrent laryngeal nerve, a finding compatible with Ortner's syndrome.
Relatamos um caso de paciente do sexo feminino, 55 anos, hipertensa, tabagista, apresentando disfonia, disfagia e tosse seca persistente. À videolaringoscopia foi observada paralisia da prega vocal esquerda. A tomografia computadorizada mostrou aneurisma sacular da parede inferior do arco aórtico, no local de deflexão do nervo laríngeo recorrente, permitindo diagnosticar a síndrome de Ortner.
ABSTRACT
AbstractThe authors report the case of a 55-year-old female, hypertensive, smoker patient presenting with dysphonia, dysphagia and persistent dry cough. Laryngoscopy diagnosed left vocal cord paralysis. Computed tomography demonstrated saccular aneurysm of the inferior wall of the aortic arch, stretching the left recurrent laryngeal nerve, a finding compatible with Ortner’s syndrome.
ResumoRelatamos um caso de paciente do sexo feminino, 55 anos, hipertensa, tabagista, apresentando disfonia, disfagia e tosse seca persistente. À videolaringoscopia foi observada paralisia da prega vocal esquerda. A tomografia computadorizada mostrou aneurisma sacular da parede inferior do arco aórtico, no local de deflexão do nervo laríngeo recorrente, permitindo diagnosticar a síndrome de Ortner.
