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Ocul Immunol Inflamm ; 26(5): 677-679, 2018.
Article in English | MEDLINE | ID: mdl-29020499

ABSTRACT

Chikungunya virus (CHIKV) is an RNA virus transmitted by Aedes mosquitoes. The clinical manifestations include fever, arthralgia, rash, and other atypical clinical findings including ocular lesions. We report the case of a 57-year-old man with meningoencephalitis and anterior uveitis due to CHIKV. The patient had developed bilateral anterior uveitis with iris atrophy and a cotton wool spot on the left eye, and his serum, urine, saliva, and cerebrospinal fluid were positive for CHIKV by RT-PCR. The spectrum of the ophthalmologic manifestations and its pathophysiology in cases of CHIKV infections needs to be better understood. Additional studies examining the ocular lesions caused by CHIKV could improve the therapeutic goals of reducing the morbidity and sequels.


Subject(s)
Chikungunya Fever/complications , Encephalitis, Viral/etiology , Eye Infections, Viral/etiology , Uveitis, Anterior/etiology , Acute Disease , Aedes/virology , Animals , Aqueous Humor/virology , Chikungunya Fever/transmission , Chikungunya Fever/virology , Chikungunya virus/genetics , Encephalitis, Viral/diagnosis , Encephalitis, Viral/virology , Eye Infections, Viral/diagnosis , Eye Infections, Viral/virology , Humans , Magnetic Resonance Imaging , Male , Microscopy, Acoustic , Middle Aged , Polymerase Chain Reaction , RNA, Viral/analysis , Tomography, Optical Coherence , Uveitis, Anterior/diagnosis , Uveitis, Anterior/virology
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