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Paediatr Anaesth ; 6(5): 361-5, 1996.
Article in English | MEDLINE | ID: mdl-8880815

ABSTRACT

The oral cavity offers a simple, painless way of drug administration. For this reason, we used oral transmucosal ketamine (5-6 mg.kg-1) for premedication in 25 children and compared it with intranasal ketamine (5-6 mg.kg-1), placebo and intramuscular ketamine (5-6 mg.kg-1). Oral transmucosal ketamine (OTK) provided effective sedation, facilitated i.v. line insertion and was accepted with pleasure by the patients (as lollipops). The lollipops produced a slight increase in gastric volumes but did not affect gastric pH. In conclusion OTK has been shown to be an effective, harmless preoperative medication in paediatric patients.


Subject(s)
Anesthetics, Dissociative/administration & dosage , Ketamine/administration & dosage , Preanesthetic Medication , Administration, Intranasal , Administration, Oral , Child , Child, Preschool , Female , Humans , Injections, Intramuscular , Male
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