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2.
Br J Neurosurg ; 21(5): 524-7, 2007 Oct.
Article in English | MEDLINE | ID: mdl-17922325

ABSTRACT

Metastasis of meningiomas due to iatrogenic implantation of tumour cells is extremely rare and only four cases have been reported to date. In this study, we report a 45-year-old female patient who presented with meningioma metastasis at the pin site of head holder applied in the original operation.


Subject(s)
Frontal Bone , Meningeal Neoplasms/surgery , Meningioma/secondary , Neoplasm Seeding , Skull Neoplasms/secondary , Adult , Cerebrospinal Fluid , Craniotomy/adverse effects , Female , Humans , Meningeal Neoplasms/diagnostic imaging , Meningioma/diagnostic imaging , Meningioma/surgery , Neoplasm Recurrence, Local/surgery , Radiography , Reoperation
3.
Neurol Med Chir (Tokyo) ; 47(3): 128-31, 2007 Mar.
Article in English | MEDLINE | ID: mdl-17384496

ABSTRACT

A 15-year-old boy presented with an extremely rare optochiasmatic cavernous angioma. He was admitted to a special hospital with the complaint of blurred vision persisting for 1 month. Magnetic resonance imaging and biopsy of the lesion were inconclusive. He was admitted to our neurosurgical clinic after worsening of the visual symptoms 9 months later. Repeat magnetic resonance imaging showed optochiasmatic cavernous angioma which had doubled in size. The lesion was removed completely without any problem. Postoperatively his visual complaints remained stable, but had improved after 1 year. Optochiasmatic cavernous malformation should be treated by surgical excision, whereas biopsy is useless and may result in enlargement.


Subject(s)
Hemangioma, Cavernous/diagnosis , Optic Chiasm , Optic Nerve Neoplasms/diagnosis , Adolescent , Humans , Male
4.
Heart Vessels ; 20(2): 66-71, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15772781

ABSTRACT

Spinal cord ischemia may develop into paraplegia in some cases during operation of the thoracoabdominal aorta. This is attributable to the vulnerability of spinal motor neurons to ischemia. In this study, iloprost was used as an agent to decrease the severity of ischemia and reperfusion injury to the spinal cord motor neurons. Twenty-one rabbits were randomized into three groups of seven animals each: group A (iloprost not administered), group B (25 ng/kg per minute iloprost), and group S (sham-operated). The spinal cord ischemia model was created by a 15-min occlusion of the aorta just caudal to the renal artery with a balloon catheter. Administration of iloprost began 10 min before occlusion of the aorta, and continued thereafter for 60 min. The pre- and postocclusion arterial pressure and heart rate recordings, results of blood gas analyses, and hematocrit and glucose levels were recorded. The spinal cords were removed after 8-h monitoring of neurologic function. Viable and nonviable motor neurons in the anterior horn of the spinal cord were counted under light microscopy. Any significant alteration in hemodynamics, blood gases, and other physiologic parameters could not be detected within the groups. Iloprost had a moderately hypotensive effect. Neurologic function in terms of Johnson scoring was significantly better in the iloprost group (P<0.05). The number of viable cells was higher, whereas the number of nonviable cells was lower in iloprost group, when compared with the control group (P<0.05). Higher numbers of viable motor neurons were consistent with the neurological findings. As a result of this study we concluded that iloprost infused during clamping of the aorta mitigates the spinal cord injury due to ischemia and reperfusion, and has a significant protective effect.


Subject(s)
Iloprost/pharmacology , Motor Neurons/drug effects , Neuroprotective Agents/pharmacology , Reperfusion Injury/prevention & control , Spinal Cord Ischemia/drug therapy , Spinal Cord/drug effects , Animals , Blood Gas Analysis , Blood Pressure/drug effects , Cell Survival/drug effects , Disease Models, Animal , Heart Rate/drug effects , Motor Neurons/pathology , Neurologic Examination , Rabbits , Reperfusion Injury/pathology , Reperfusion Injury/physiopathology , Spinal Cord/pathology , Spinal Cord Ischemia/pathology , Spinal Cord Ischemia/physiopathology , Time Factors
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