ABSTRACT
Addison's disease is due to an insufficiency of corticosuprarrenal hormones to maintain the peripheral needs and its clinical sign is a constitutional syndrome with cutaneous hyperpigmentation and low blood pre-assure. The ethiology has drastically variated in the last century; being the origin almost exclusively tuberculous at the beginning of 1900 and mainly autoimmune actually. Nowadays it is difficult to understand Addison's disease out of the context of autoimmune polyglandular syndromes in view of the frequent association to other endocrinopathies. The present article pretend to realize a vision of the global disease related to these multiple endocrine deficits.
Subject(s)
Addison Disease , Addison Disease/diagnosis , Addison Disease/epidemiology , Addison Disease/physiopathology , Addison Disease/therapy , HumansABSTRACT
La enfermedad de Addison se caracteriza por una oferta insuficiente de hormonas corticosuprarrenales para mantener las demandas periféricas y cursa como un síndrome constitucional con melanodermia e hipotensión. Su etiología ha variado drásticamente en el último siglo, siendo a comienzos de 1900 de origen casi exclusivamente tuberculoso y en la actualidad mayoritariamente autoinmune. Es difícil entender hoy la enfermedad de Addison sino es en el contexto de los Síndromes Poliglandulares Autoinmunes, dada la frecuente asociación con otras endocrinopatías. El presente artículo pretende realizar una visión de la enfermedad global en relación con esos déficits endocrinos múltiples (AU)
Subject(s)
Humans , Addison Disease/epidemiology , Addison Disease/etiology , Polyendocrinopathies, Autoimmune , Addison Disease/physiopathology , Addison Disease/therapyABSTRACT
La enfermedad de Addison se caracteriza por una oferta insuficiente de hormonas corticosuprarrenales para mantener las demandas periféricas y cursa como un síndrome constitucional con melanodermia e hipotensión. Su etiología ha variado drásticamente en el último siglo, siendo a comienzos de 1900 de origen casi exclusivamente tuberculoso y en la actualidad mayoritariamente autoinmune. Es difícil entender hoy la enfermedad de Addison sino es en el contexto de los Síndromes Poliglandulares Autoinmunes, dada la frecuente asociación con otras endocrinopatías. El presente artículo pretende realizar una visión de la enfermedad global en relación con esos déficits endocrinos múltiples (AU)
No disponible
Subject(s)
Humans , Addison Disease/epidemiology , Addison Disease/physiopathology , Polyendocrinopathies, Autoimmune/epidemiology , Renal Insufficiency/complications , Addison Disease/etiologyABSTRACT
We report the case of a patient with Turner's syndrome, whose special peculiarity is that its clinical signs have gone unnoticed despite the presence of several morphological features and functional disorders which must have induced it precociously. It's about a 58 years old patient with an aortic metalic valve in treatment with dicumarinics, who came to emergencies with a severe anemic syndrome because of a peptic ulcer propitiated by the hypoprotrombinaemia. In the physical examination some typical signs of the syndrome were detected. The karyotype verified the existance of Turner (45X0). We insist on the need of an early diagnosis, in order to prevent the short stature and to offer a satisfactory sexual development, and we include an actualization of the different approachments in the therapy and management of the disease.
Subject(s)
Turner Syndrome/diagnosis , Turner Syndrome/therapy , Female , Humans , Karyotyping , Middle Aged , Time Factors , Turner Syndrome/geneticsABSTRACT
No disponible
Subject(s)
Middle Aged , Adult , Male , Female , Humans , Cryptogenic Organizing Pneumonia , Necrosis , Anti-Arrhythmia Agents , Amiodarone , MediastinitisABSTRACT
Presentamos el caso de una paciente portadora de Síndrome de Turner, cuya especial peculiaridad es la de haber pasado desapercibido su cuadro clínico, realizándose un diagnóstico tardío, no obstante la presencia de diversos rasgos morfológicos y alteraciones funcionales que debieran haberlo evocado precozmente. Se trata de una paciente de 58 años con prótesis metálica por aorta bicúspide estenótica, en tratamiento con dicumarínicos, que acudió a urgencias con severo síndrome anémico por ulcus péptico sangrante propiciado por hipoprotrombinemia. En la exploración se detectaron una serie de rasgos característicos de la enfermedad. El cariotipo confirmó la presencia de Síndrome de Turner (45 XO). Se insiste en la necesidad de un diagnóstico precoz, única posibilidad de intentar prevenir el déficit estatural y ofrecer un desarrollo madurativo sexual adecuado (AU)
Subject(s)
Female , Middle Aged , Humans , Mouth , Karyotyping , Time Factors , Turner Syndrome , Turner Syndrome/diagnosis , Turner Syndrome/genetics , Turner Syndrome/therapyABSTRACT
Until now, the care of HIV patients, essentially were in the hospital; but the increase in the number of this and the news aspects of them have conditioned changes in the form of assistance. The primary assistance of this patients include prevention, precocious diagnostics, control of assymptomatics patients and diagnosticand-treatment of complications. The last important aspect is home care of terminal patients whose the hospitable assistance is not beneficial as soon as the family support.
Subject(s)
Acquired Immunodeficiency Syndrome/therapy , Home Care Services , Terminal Care , Acquired Immunodeficiency Syndrome/complications , Clinical Protocols , Humans , Palliative CareABSTRACT
Acute dissection of the aorta is a relatively frequent clinical entity, with a poor prognosis and a global mortality of 40% during the first 48 hours. A correct diagnosis and an early surgical treatment may modify the natural course of the dissection of aorta. We present a case of a patient with high clinical suspicion in the aortography, thoraci CAT and transthoracic echocardiogram (TTE). However, it was not possible to establish the diagnosis. The transesophagic echocardiogram (TEE), on the contrary, suggested the presence of dissection of aorta, as was later verified in the necropsis methods, seems to support the TEE as the first election method in the dissection of aorta.
