ABSTRACT
In the current study the argyrophil staining technique for NOR proteins (Ag-NORs) has been performed on cases of different endometrial lesions, trying to find an aid in differentiating atypical hyperplasia from well differentiated carcinoma in biopsy specimens. We conclude that the Ag-NOR count, even though in endometrial carcinoma is significantly exceeding that of atypical hyperplastic endometrium, could be a misleading discriminator, because of a wide overlap of values in individual cases.
Subject(s)
Carcinoma/metabolism , Endometrial Neoplasms/metabolism , Endometrium/metabolism , Nucleolus Organizer Region/metabolism , Endometrial Neoplasms/pathology , Endometrium/pathology , Female , Humans , Hyperplasia/metabolism , Proteins/analysis , Silver StainingABSTRACT
Three new cases of benign lipomatous lesions of the uterus are described, with particular attention to the possible relation between symptomatology and the presence of mast cells in the neoformation. The literature is reviewed, a brief history is presented of important stages in the study of these forms, and a new histogenetic theory proposed based on a different concept from those accepted to date.
Subject(s)
Lipoma/pathology , Uterine Diseases/pathology , Adipose Tissue/pathology , Aged , Aged, 80 and over , Female , Humans , Metaplasia , Middle AgedSubject(s)
Neoplasms/epidemiology , Registries , Adolescent , Adult , Aged , Female , Hospitals , Humans , Italy , Male , Middle AgedABSTRACT
2 cases of supernumerary breast tissue in the vulva observed in pregnant women are reported. The mammary tissue showed histological features typical of the lactating breast and immunohistochemical evidence of milk protein production.
Subject(s)
Breast , Choristoma/pathology , Lactation , Pregnancy Complications, Neoplastic/pathology , Vulvar Neoplasms/pathology , Adult , Choristoma/analysis , Female , Humans , Milk Proteins/analysis , Pregnancy , Pregnancy Complications, Neoplastic/analysis , Vulva/pathology , Vulvar Neoplasms/analysisSubject(s)
Autopsy , Data Collection , Death Certificates , Neoplasms/diagnosis , Registries , Diagnostic Errors , Humans , Italy , Neoplasms/epidemiologySubject(s)
Neoplasms/epidemiology , Registries , Age Factors , Hospitals, General , Humans , Italy , Sex FactorsABSTRACT
This paper reports the results of cervico-vaginal examinations performed on the women (7,098) resident in the municipality of Bollate (mass screening) and the women (1,416) hospitalized in the Gynecologic ward in the same period (in-patients). Age distribution, prevalence of initial and invasive forms, and prevalence according to age groups have been considered. The results are: 1) any kind of lesion is more frequent among in-patient than mass-screening subjects; 2) the prevalence of benign displasia, incipient, in situ and invasive carcinoma per age group, considered per quinquennium, shows a three-phase trend, both in mass screening and in-patient cases; 3) the time of evolution is different for cervicocarcinoma in the different age groups of incipience. Periodic checks are a useful means of precocious diagnosis of cervicocarcinoma; the frequency of checks should vary according to patient age.