ABSTRACT
Microbiological analysis of a urine sample from an outpatient with symptoms of urinary infection detected >10(5) CFU/mL urine of Salmonella enterica serotype Virchow with resistance to cefotaxime. Molecular analysis demonstrated the presence of the gene encoding CTX-M-10 beta-lactamase in this clinical isolate. This is the first report of this enzyme in Salmonella spp.
Subject(s)
Salmonella enterica/enzymology , beta-Lactamases/metabolism , Adult , Anti-Bacterial Agents/pharmacology , Bacterial Typing Techniques , Cefotaxime/pharmacology , Drug Resistance, Microbial , Escherichia coli/metabolism , Female , Humans , Salmonella Infections/microbiology , Salmonella enterica/drug effects , Salmonella enterica/genetics , Urinary Tract Infections/microbiology , beta-Lactamases/geneticsABSTRACT
In total, 320 vaginal or rectal swabs were cultured on Granada medium (GM) or Group B Streptococcus Differential Agar (GBSDA), and were also inoculated into LIM broth (Todd-Hewitt broth supplemented with selective antibiotics), for detection of group B Streptococcus (GBS). Overall, GBS isolates were detected on 53 of the 320 swabs; 47 of these isolates grew on both GM and GBSDA, five only on GBSDA, and one only following subculture from LIM broth. GBSDA appears to be a valid alternative to GM for the growth of GBS isolates from pregnant women.
Subject(s)
Agar , Culture Media , Pregnancy Complications, Infectious/microbiology , Streptococcal Infections/microbiology , Streptococcus agalactiae/isolation & purification , Bacteriological Techniques , Female , Humans , Pregnancy , Rectum/microbiology , Specimen Handling/methods , Streptococcus agalactiae/growth & development , Vagina/microbiologyABSTRACT
Between October 2001 and August 2002, 30 hospital patients became infected or colonised by a multiresistant (including to carbapenems) epidemic strain of Acinetobacter baumannii (AbMR) in a hospital outbreak. This study analysed the risk-factors associated with acquisition of this epidemic strain and investigated the prognosis of patients infected by AbMR, with the aim of elucidating factors which lead to mortality. A case-control study of the acquisition of AbMR in patients infected or colonised in the hospital outbreak was performed. Independent risk-factors leading to death were studied by logistic regression analysis. Multivariate analysis of the risk-factors for colonisation/infection with AbMR revealed an independent association with the presence of an arterial catheter (OR, 1.13; 95% CI, 1.03-1.25) and administration of imipenem as monotherapy (OR, 11.12; 95% CI, 2.33-53.09). Multivariate analysis of the prognostic features leading to mortality revealed a significant association with hypotension or shock (OR, 24.63; 95% CI, 1.56-387.56) at the time of bacterial isolation.
