ABSTRACT
In a double-blind, randomized plan of drug administration, nalbuphine, fentanyl, and a placebo were compared for efficacy in sedation and analgesia during third molar removal. Fifty-eight patients participated in this study. Using accepted intravenous sedation and surgical techniques, fentanyl and nalbuphine were found to be better than placebo for anxiety and pain control in third molar surgery. Fentanyl had a longer duration of pain relief postoperatively than did nalbuphine. The study confirmed the need for a narcotic supplement to sedation techniques for third molar surgery.
Subject(s)
Analgesics , Fentanyl/therapeutic use , Molar, Third/surgery , Morphinans/therapeutic use , Nalbuphine/therapeutic use , Tooth Extraction , Tooth, Impacted/surgery , Clinical Trials as Topic , Diazepam , Double-Blind Method , Humans , Male , Patient Compliance , Placebos , Preanesthetic Medication , Random AllocationABSTRACT
There are two discrete lobes comprising the armadillo submandibular gland. These two lobes can be defined grossly, histochemically and morphologically with the light and electron microscope. The minor lobe stains more intensely with PAS and AB. When viewed in the electron microscope, the secretory granules of the acinar cells within this lobe appear mucous-like. The granules of the demilune cells are slightly different in appearance. The secretory granules of the acinar cells in the major lobe contain many dense foci embedded in a fibrillar matrix, a substructure not described previously. The demilune cells of this lobe contain secretory granules with a mucous-like structure which is consistent throughout the entire lobe. As in the minor lobe, these demilune cells stain very intensely with PAS and AB.
