ABSTRACT
Cholangioblastic variant of cholangiocarcinoma is rare and may be encountered in young adults with a liver mass. On biopsy, the pathologic features may mimic neuroendocrine or other tumors. Increased awareness of this unusual variant and the typical strong expression of the immunohistochemical marker inhibin may help prevent diagnostic errors. Because only a few cases have been reported, we also discuss treatment options in a 26-year-old man.
Subject(s)
Cough/diagnosis , Dyspnea/diagnosis , Giant Cells/pathology , Lymphadenopathy/diagnosis , Sarcoidosis, Pulmonary/diagnosis , Adult , Biopsy, Fine-Needle , Bronchoalveolar Lavage Fluid/cytology , Chronic Disease , Cough/pathology , Dyspnea/pathology , Histiocytes/pathology , Humans , Lymphadenopathy/pathology , Male , Papanicolaou Test , Sarcoidosis, Pulmonary/pathologyABSTRACT
In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide. The incidence of CDI has also increased in surgical patients. Optimization of management of C difficile, has therefore become increasingly urgent. An international multidisciplinary panel of experts prepared evidenced-based World Society of Emergency Surgery (WSES) guidelines for management of CDI in surgical patients.
ABSTRACT
Diverticulitis and Clostridium difficile infection (CDI) are common conditions in the surgical population. However, they are usually 2 distinct clinical entities. Here, we report the case of acute diverticulitis with concomitant pseudomembranous colitis, presumably due to CDI. The clinical course as well as gross and microscopic pathology findings are discussed. A literature search revealed a single previous report of these findings concomitant in a surgical specimen. A brief discussion of the pathophysiology of CDI and acute diverticulitis is included.
