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Comput Math Methods Med ; 2015: 891692, 2015.
Article in English | MEDLINE | ID: mdl-25737739

ABSTRACT

A novel clustering method is proposed for mammographic mass segmentation on extracted regions of interest (ROIs) by using deterministic annealing incorporating circular shape function (DACF). The objective function reported in this study uses both intensity and spatial shape information, and the dominant dissimilarity measure is controlled by two weighting parameters. As a result, pixels having similar intensity information but located in different regions can be differentiated. Experimental results shows that, by using DACF, the mass segmentation results in digitized mammograms are improved with optimal mass boundaries, less number of noisy patches, and computational efficiency. An average probability of segmentation error of 7.18% for well-defined masses (or 8.06% for ill-defined masses) was obtained by using DACF on MiniMIAS database, with 5.86% (or 5.55%) and 6.14% (or 5.27%) improvements as compared to the standard DA and fuzzy c-means methods.


Subject(s)
Breast Neoplasms/pathology , Mammography/methods , Radiographic Image Interpretation, Computer-Assisted/methods , Algorithms , Breast Neoplasms/diagnostic imaging , Cluster Analysis , Databases, Factual , Female , Fuzzy Logic , Humans , Models, Statistical , Normal Distribution , Pattern Recognition, Automated/methods , Probability , Reproducibility of Results
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