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For adapting the continuing reform of our medical care structure, further developing the standardize of the private dental clinics in China, in this article the key elements of the dental clinic management were presented, to emphasize the importance of medical service concept re new and team work build-up, also the clinic model of the modern dentistry was discussed.
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OBJECTIVE: Observation of clinical results and SEM features in treatment of hypersensitive dentine by semiconductor laser.METHODS:Semiconductor laser was compared with conventional NaF method for the treatment of 100 teeth with typical hypersensitive dentine which were divided into two groups.RESULTS:The efficiency of the laser group was 96%,while that of NaF group was 76%.The laser irradiation could decrease hypersensitive dentive. There was marked difference between two groups.It was testified by SEM that the dentinal tubule was sealed by semiconductor laser irradiation.CONCLUSION:The safe,effective and easy methods was provided for treating the hypersentitive dentive by use of semiconductor laser.
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OBJECTIVE:In order to study cellular dynamicfeatures in carcinoma and premalignancy originated inepithelial tissue. METHODS: The golden hamster pouch premalignant model with dimethylbenzanthracence(DMBA) smeared was established by Salley and detected with flow cytometry(FCM) binding to bromodeoxyuridine(BRDU),30 Syrian golden hamsters were grouped and done contrast study. RESULTS: The cellular lesions were aggravated gradually along with extention of smeared DMBA microstopically,FCM detective results demonstrated that the detective rate of Sporiod cell between contrast and smeared group had significant difference. Even though mild dysplsia presented microscopically FCM detective result and significant difference. CONCLUSION: The study suggests that golden hamster cheek pouch premalignancy has cellular dynamicfeatures of dysplasia.
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OBJECTIVE:In this study that the DMBA was applicated to induce the premalignantal changes of the cheek pouches of 89 hamsters in various stage,the result was shown that the slight epithelial displasia was occured 3 weeks later,the medium displasia was occured 5 weeks later,and the severe displasia or the carcinoma in situ was occured 6-9 weeks later.It is suggested that the suitable experimental period of the hamster's carcinogenesis is during 1-3 weeks.
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109 cases were studied by immunohistochemisty with anti-PCNA antibody specimens which dyed by PCNA immunohistochemistry were counted with net and morphology observed.The results indicated that:a few of PCNA-positive cells had been seen in the basal cells of normal epithelium. An increased percentage of PCNA-positive cells was found in dysplasia and carcinoma.The increase between every grade is of statistical significance(P<0.05).In slight dysplasia grade group,the percentage od PCNA-positive cells increasing between applying DMBA-six-weeks' group is of statistical significance(P<0.05),and hadn't found statistical difference among the other groups.It is demonstrated that PCMA is one of criteria which were observed cell reproduction reactivities during precarcinoma,and it is more sensitive than light microscopy.
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Clinic pathology and detection using IGSS of 201 cases of discoid lupus erythematosus (DLE) were studied in this paper.The results showed:1.DLE usually occured on the low lip(60%);2.Suffering from gastrointestinal disease were the first symptom(25%DLE cases was confirmed by mild dysplasia,3 cases of carcinoma.1 cases Combined of DLE and lichen planus(LP);4.Immunogold-silver Staining (IGSS) was applied to detect immune complex.The result indicated that Fg,immunoglobins and complement C3 deposited at basal membrane zone of DLE.It is illustrated that DLE is an autoimmune disease which is caused by many kinds of factors and may be cancerous.Coexistence of DLE and LP suggested that they may be at different stages of the same disease.Its mechanism will be further studied.
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In this study,single blind grouping method was applied to compare the effect of chloroquine and triamcinolone-A which were used to treat 360 cases of oral lichen planus.The results showed the effect of local injecting triamcinolone-A was better than that of taking chloroquine,and also was better than that of taking triamcinolone-A accompained of chloroquine.Therefore,they were two effective ways to cure OLP and worthy of wide use.
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This study was reviewing in analysed the clinical,histopathological and treatment features of 39 cases suffered in oral mucosal hyperplasia.It definited the sorts of disease which may be malignant changed and the histopathological grading criteria of hyperplasis.The different treatment methods were administered according to the different grade of the malignant change.The results of the post-treatment observation showed that the drug method only be fit for the cases suffered slight hyperplasia without nuclei differentiation.
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Immuno-gold and silver staining (IGSS) is an advanced labelling method followed by Immuno-fluorescence(IF),Immunoenzyme and Radio-immunity.In this study,the IGSS method for detection of deposits of Immunogloblins (IgG,IgA,IgM) at the BMZ had been performed on biopsy specimens from oral lesion of patients with OLP and DLE.The results indicated that the sensitivity and specificity of IGSS were super than that of DIF.It suggested the IGSS be an available method to detect oral mucosal diseases widely.
