ABSTRACT
INTRODUCTION: Blister-like aneurysms (BAs) are usually defined as arterial lesions arising from nonbranching sites on intracranial arteries. Because of specific peculiarities such as different pathophysiology, fragility of the aneurysmal wall, high risk of intraoperative bleeding, and high probability of losing parent vessel patency, their treatment is controversial, and both endovascular and surgical options have been reported. METHODS: From 2006 to 2015 (10 years), 7 aneurysms in 6 patients were treated. We retrospectively reviewed the records of these patients to analyze clinical pictures and outcomes, which are expressed as modified Rankin Score. RESULTS: In our sample of 7 aneurysms in 6 patients, all BAs were successfully treated (complete exclusion in 100% on follow-up angiography). A good outcome (modified Rankin Score = 0) was achieved in all patients, with no difference related to aneurysm size and location. There was no mortality. CONCLUSIONS: Surgical treatment of BAs may be effective and have acceptable complications and outcomes.
Subject(s)
Intracranial Aneurysm/surgery , Neurosurgical Procedures , Adult , Female , Humans , Intracranial Aneurysm/diagnostic imaging , Male , Middle Aged , Retrospective StudiesABSTRACT
Morquio A syndrome (Online Mendelian Inheritance in Man #253000) is a lysosomal storage disease caused by deficiency of N-acetylgalactosamine-6-sulfatase encoded by the GALNS gene. Key clinical features are skeletal dysplasia and short stature.
