ABSTRACT
Ostial left anterior descending artery stent implantation was performed, while trying to cross another stent through the left main coronary artery into the left circumflex artery the stent was detached from the delivery balloon, subsequently jamming the stent of the ostial left anterior descending artery stent. Removing the detached stent was possible, but longitudinal compression of the ostial left anterior descending artery stent occurred. We finally took advantage of the longitudinal compression to advance the equipment into the left circumflex artery with good final result.
Subject(s)
Angioplasty, Balloon, Coronary , Coronary Artery Disease/therapy , Coronary Vessels/diagnostic imaging , Drug-Eluting Stents/adverse effects , Intraoperative Care , Prosthesis Retention , Aged , Angioplasty, Balloon, Coronary/adverse effects , Angioplasty, Balloon, Coronary/instrumentation , Angioplasty, Balloon, Coronary/methods , Coronary Angiography/methods , Coronary Artery Disease/complications , Coronary Artery Disease/diagnosis , Coronary Artery Disease/physiopathology , Coronary Vessels/physiopathology , Equipment Failure , Humans , Hypertension/complications , Intraoperative Care/adverse effects , Intraoperative Care/methods , Male , Prosthesis Retention/adverse effects , Prosthesis Retention/methods , Treatment OutcomeABSTRACT
Adequate long-chain polyunsaturated fatty acid (LCP) status during pregnancy is important. We studied the effect of three low-dose fish oil supplements, administered during uncomplicated pregnancy, on neonatal LCP status at term delivery. Supplements were administered from the second trimester to delivery, either as fish oil capsules ("fish-1": 336 mg LCPomega3, n=15; and "fish-3": 1,008 mg LCPomega3, n=20) or milk-based supplement ("Mum": 528 mg LCPomega3, n=24). Fifty-seven untreated women served as controls. Fatty acids of umbilical veins (UV) and arteries (UA) were measured. The fish-1 group showed no differences, compared to controls. The Mum group had higher 20:5omega3, 22:5omega3, 22:6omega3, LCPomega3 and 22:6omega3/22:5omega6 in UV and UA. The fish-3 group had higher 22:5omega3 and 22:6omega3 (UA), LCPomega3 and 22:6omega3/22:5omega6 (UV and UA) and 20:3omega6 (UV). A 500-1000 mg daily LCPomega3 supplement, taken either as a milk-based supplement or fish oil capsules, effectively increases fetal LCPomega3 status, without affecting LCPomega6 status.
Subject(s)
Dietary Supplements , Fatty Acids, Unsaturated/blood , Fetal Blood/chemistry , Fish Oils/administration & dosage , Maternal-Fetal Exchange , Adult , Birth Weight , Female , Gestational Age , Humans , Infant, Newborn , Pregnancy , Umbilical Arteries , Umbilical VeinsABSTRACT
OBJECTIVE: To compare serum levels of angiogenic growth factors vascular endothelial growth factor (VEGF), placental growth factor (PlGF) and angiogenin in pre-eclamptic women and matched controls. DESIGN: Retrospective analysis of -70 degrees C stored serum of women who developed pre-eclampsia and matched controls. SETTING: Department of Gynaecology and Obstetrics, St Elisabeth Hospital, Curaçao, Netherlands Antilles. SAMPLE: Thirty women with pre-eclampsia and 30 normotensive controls matched for age and gestation. RESULTS: VEGF and PIGF serum levels were significantly lower in pre-eclamptic pregnancies, compared with controls (VEGF 0.31 +/- 1.20 vs 18.30 +/- 24.97 pg/mL, P = 0.0004; PlGF 54.19 +/- 32.05 vs 497.95 +/- 340.51 pg/mL, P < 0.0001). Matched couple analysis showed VEGF serum concentrations to be lower in the majority of pre-eclamptic women and PlGF concentrations to be lower in all pre-eclamptic women. Angiogenin serum levels showed no statistical significant difference between pre-eclamptic pregnancies and controls (523.68 +/- 367.55 vs 670.41 +/- 251.54 ng/mL, P = 0.058), with matched couple analysis showing no clear pattern. CONCLUSIONS: Decreased serum levels of VEGF and PIGF characterise, and therefore seem to be of importance during (the development of), pre-eclampsia. This selective deficit of angiogenic growth factors might in part explain the shallow placentation found in this pregnancy complication.
