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1.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 1-7, 2020.
Article in English | MEDLINE | ID: mdl-33541060

ABSTRACT

Sander bite jumping appliance (BJA) is a functional appliance used to correct Class II malocclusion in growing patients. The aim of this study was to identify the dento-skeletal effects in patients treated with BJA before growth peak and to compare these effects with the ones obtained in a similar group treated with the Andresen activator (AA). Twenty subjects with class II relationship of the skeletal bases and cervical vertebrae maturation stage 1 or 2 were enrolled in the study and treated with BJA. This group were compared to 14 subjects treated with AA. Cephalometric analyses were carried out using landmarks derived from the analyses of Pancherz, Ricketts, Tweed and Steiner. After treatment with BJA Pg/OLp increase was 7.40±3.81 mm (P<0.001); Pg/OLp+Co/OLp significantly heightened from T0 to T1 (T0: 82.20±4.65 mm vs T1: 89.62±4.27, P<0.001). Overjet (is/OLp - ii/OLp) significantly decreased from T0 to T1 (T0: 7.40±2.31 mm vs T1: 3.05±1.34 mm, P<0.001). Molar relationship improved passing from 1.46±1.68 mm at T0 to -3.56±2.04 mm at T1 (P<0.001). No statistically significant differences were found between BJA and AA groups at T0 and T1. BJA treatment determined a Class II malocclusion correction in all patients. The correction of molar relationship was mainly due to the increase in mandibular length; the correction of the overjet was due to the increase in mandibular length, to the slight pro-inclination of the lower incisors and the mild retro-inclination of the upper incisors. No significant differences were found in effectiveness between BJA and AA.


Subject(s)
Malocclusion, Angle Class II/therapy , Cephalometry , Humans , Incisor , Mandible
2.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 9-20, 2020.
Article in English | MEDLINE | ID: mdl-33541061

ABSTRACT

The atrophic posterior ridges are usually characterized by poor bone quality and quantity: this situation requires the use of bone regenerative techniques. Other alternative surgical approaches are investigated. Nowadays the use of trans-sinus implants offers some advantages due to its feasibility. Today, bone grafting may be practical, but depends on many factors, such as the type of bone graft used (autogenous, alloplastic, or xenograft), host response, age of the patient, various complications associated with grafting procedures, infection, and, most importantly, the time spent while the grafted material matures and is taken up by the bone. So, this case report describes the feasibility of an alternative surgical technique associated to PRP (Platelet Rich Plasma).


Subject(s)
Dental Implants , Maxilla/surgery , Maxillary Sinus/surgery , Platelet-Rich Plasma , Bone Regeneration , Bone Transplantation , Humans
3.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 37-48, 2020.
Article in English | MEDLINE | ID: mdl-33541063

ABSTRACT

Medication-related osteonecrosis of the jaw (MRONJ) is a major disease under study for over the last twenty years. Different classifications have been proposed and many therapies for the different stages have been applied. The evolution of treatments lead to an increasingly conservative approach. Numerous adjuvant treatments have been proposed in the last decade. All these complementary treatments have been proposed mainly to resolve or reduce the painful stress, predominantly caused by bacterial infection, simplifying the wound healing process and improving patients' compliance. Nowadays "secondary" treatments, such as autologous platelet concentrates (APCs, more specifically PRP, PRGF or PRF), hyperbaric oxygen (HBO), Auto/tetracycline fluorescence-guided bone surgery (AF-GBS/TF-GBS), medical drugs like teriparatide or the combination between pentoxifylline and tocopherol, fluorodeoxyglucose positron emission tomography (FDG-PET), laser and/or low-laser therapy and ozone therapy are more or less well documented and known considering their clinical effectiveness. The aim of the present review is the evaluation of the quantity and quality of scientific studies concerning this specific topic.


Subject(s)
Bisphosphonate-Associated Osteonecrosis of the Jaw/diagnosis , Bisphosphonate-Associated Osteonecrosis of the Jaw/therapy , Anti-Bacterial Agents/therapeutic use , Bone Density Conservation Agents/adverse effects , Diphosphonates/adverse effects , Humans , Laser Therapy , Tocopherols/therapeutic use , Treatment Outcome
4.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 49-61, 2020.
Article in English | MEDLINE | ID: mdl-33541064

ABSTRACT

The introduction of computer-assisted and guided surgery has radically improved the possibility of using all available bone for implant support, reducing the need for extensive grafting procedures and allowing for better implant placement and restoration. Moreover, fresh frozen homologous bone (FFB) grafts have shown good osteoconductive properties and biocompatibility with results comparable to autologous bone patients. The purpose of this retrospective cohort study was to evaluate the survival and the success rate of implants and related fixed full arch prosthesis at the 5 to 8 years follow-up when performed with immediate function using a flapless surgical procedure and computer-aided technology (NobelGuide®, Nobel Biocare® AB, Goteborg, Sweden) in patients previously treated with FFB grafts; treated at the University of Verona with the NobelGuide® system from January 2007 to December 2012 with at least 5 years follow-up were reviewed. Survival implants and survival prosthesis' percentage reached 95% in a 5 to 8-year period. This study indicates that patients previously augmented with FFB graft for maxillary or mandibular bone atrophy can be safely treated with implant supported prosthesis based on the NobelGuide® protocol, with the aid of computer-generated guide.


Subject(s)
Dental Implants , Surgery, Computer-Assisted , Follow-Up Studies , Humans , Retrospective Studies , Sweden , Treatment Outcome
5.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 63-68, 2020.
Article in English | MEDLINE | ID: mdl-33541065

ABSTRACT

The infant, like the young un-cooperative or odontophobic patient, constitute the most complex type of patient to be treated and it is frequent in modern society. The treatment of these patients is necessary to resolve the infectious-antalgic urgency and subsequently to build the patient/doctor relationship for continuing general dental care. Conscious sedation is the only way to approach this type of patient. Where therapeutic success with traditional sedation techniques is not achieved, as frequently happens in these patients, sedation with ketamine is the extreme ratio for the purpose of effective resolution of the dental problem, obviously carried out within facilities authorized for these anesthesiological modalities such as private outpatient surgery structures where, when necessary, it is possible to carry out the treatments also under general anesthesia as well as with ketamine.


Subject(s)
Anesthesia, Dental/methods , Dentistry/methods , Ketamine/therapeutic use , Anesthesia, General , Child , Conscious Sedation , Humans , Infant
6.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 69-76, 2020.
Article in English | MEDLINE | ID: mdl-33541066

ABSTRACT

Bisphosphonate Related Osteonecrosis of the Jaw (BRONJ) is a pathology initially described in the early 2000s that has become increasingly common in clinical dentistry and maxillofacial practice due to the frequent use of bisphosphonates medical drugs (BPs) to treat various diseases such as osteoporosis, Paget's syndrome, osteomyelitis and in bone metastases secondary to tumors. Supragingival irrigation applied as monotherapy and in combination with root planning or BFs related bone necrosectomy revealed that supragingival irrigation with a variety of agents reduced the gingival microbial load and gingival inflammation. In this 4-year follow-up study we analyze the use of hydrogen peroxide (H2O2) as an antimicrobial agent for maintenance periodontal health, improving the longevity of teeth and oral cavity healing process.


Subject(s)
Alveolar Bone Loss/drug therapy , Bisphosphonate-Associated Osteonecrosis of the Jaw/complications , Hydrogen Peroxide/administration & dosage , Hydrogen Peroxide/pharmacology , Mandibular Nerve , Periodontal Diseases/complications , Periodontal Diseases/drug therapy , Bone Density Conservation Agents/adverse effects , Diphosphonates/adverse effects , Follow-Up Studies , Humans , Osteonecrosis/drug therapy
7.
J Biol Regul Homeost Agents ; 34(6 Suppl. 2): 89-100, 2020.
Article in English | MEDLINE | ID: mdl-33541068

ABSTRACT

The rehabilitation of maxillary bone atrophy represents one of the main challenges of modern oral implantology. The use of zygomatic implants in the prosthetic rehabilitation of the patient affected by severe maxillary bone atrophy is another therapeutic alternative, not exempt from complications. The present study included 19 patients with edentulous maxillae who were treated between 2013 to 2015 with at least two zygomatic implants at the Department of Maxillofacial Surgery, Verona, Italy. The purpose of this retrospective longitudinal study was to evaluate sinus complications and radiological, periodontal and prosthetic evaluations of zygomatic implants technique in severe atrophic. Implant-prosthetic rehabilitation of the upper jaw edentulous severely atrophic using zygomatic implants represents one safe and repeatable technique. In terms of implant survival from our study showed an implant CRS (common reporting standard) of 98.5% and a prosthetic CRS 100% with a mean follow-up period of 19.2 months (range). Both recorded data are superimposed on major reported studies in literature.


Subject(s)
Dental Implants , Maxilla/surgery , Maxillary Sinus/pathology , Prosthodontics , Atrophy/pathology , Follow-Up Studies , Humans , Italy , Longitudinal Studies , Maxilla/diagnostic imaging , Maxilla/pathology , Retrospective Studies , Treatment Outcome , Zygoma/diagnostic imaging , Zygoma/surgery
8.
Radiol Med ; 71(10): 657-64, 1985 Oct.
Article in Italian | MEDLINE | ID: mdl-4089247

ABSTRACT

One hundred thirteen children referred for chronic constipation were examined by means of diagnostic work-up including anal inspection, rectal exploration, weekly bowel frequency evaluation, measurement of total and segmental intestinal transit times (TITT, SITT), contrast enema, anorectal manometry (ARM), suction rectal biopsy for histochemistry. Final diagnosis were: chronic functional "simple" constipation in 53 children; chronic functional constipation and soiling in 32; Hirschsprung's disease in 18. In 10 children, initially referred for constipation, TITT was in the normal range so they underwent no further examination. Conclusions are that bowel frequency identifies a real gastrointestinal problem, but definite diagnosis of constipation is relied on TITT. In the assessment of chronic constipation nature, ARM is more sensitive than radiology. Suction rectal biopsy is reliable in detection of aganglionosis: its accuracy can be improved by histochemical or biochemical determination of Acetylcholinoesterase.


Subject(s)
Constipation/diagnostic imaging , Intestines/diagnostic imaging , Acetylcholinesterase/analysis , Adolescent , Anal Canal/physiology , Barium Sulfate , Biopsy , Child , Child, Preschool , Constipation/diagnosis , Constipation/etiology , Enema , Female , Hirschsprung Disease/diagnosis , Hirschsprung Disease/diagnostic imaging , Humans , Infant , Intestinal Mucosa/enzymology , Male , Manometry , Radiography , Rectum/enzymology , Rectum/pathology , Rectum/physiology
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