ABSTRACT
We present 84 pregnancies (3 twin pregnancies) of 80 women with Systemic Lupus Erythematosus. Although there was a multidisciplinary prenatal control, in 83% of the cases there were one or more complications during pregnancy, most of them being preterm labor, premature rupture of membranes and preeclampsia-eclampsia. There were flares up in 15 of 84 cases, (17.85%). Worsening of renal function was the most common finding. There were 9 abortions, 3 stillbirths, 1 neonatal death and two newborns with congenital heart block. No maternal deaths were present.
Subject(s)
Lupus Erythematosus, Systemic , Pregnancy Complications , Abortion, Spontaneous/etiology , Adult , Eclampsia/etiology , Female , Fetal Death/etiology , Fetal Membranes, Premature Rupture/etiology , Heart Block/etiology , Humans , Infant, Newborn , Lupus Erythematosus, Systemic/complications , Obstetric Labor, Premature/etiology , Parity , Pre-Eclampsia/etiology , Pregnancy , Pregnancy, Multiple , Prenatal DiagnosisABSTRACT
The Hallermann-Streiff syndrome is characterized by dyscephaly (bird like facies), microphthalmia, cataracts, micrognathia, beaked nose, abnormal dentition, hypotrichosis, cutaneous atrophy and proportional small stature. There is no sex predilection. Productive capacity has not been studied in these patients. Successful pregnancy is rare. We present a patient with the classical signs associated with pregnancy, the outcome of which was successful. This is the first reported case of Hallermann-Streiff syndrome associated with pregnancy.
Subject(s)
Hallermann's Syndrome , Pregnancy Complications , Adult , Apgar Score , Cesarean Section , Female , Gestational Age , Humans , Infant, Newborn , Male , Pregnancy , Pregnancy Outcome , Sterilization, TubalABSTRACT
This is a report on the institutional experience of the use of Human Menopausal Gonadotropins (HMG) in anovulatory women diagnosed as hypothalamic-hypophysiary dysfunction of Group II of WHO with previous failure to chlomifen citrate therapy. In a period of three years 180 patients were gathered with 420 cycle of treatment, obtaining ovulation in 340 cycles (81%). The ovarian hyperstimulation syndrome (OHS) was present in 15 cases (3.5%). There were 115 pregnancies that correspond to 33.8% of oculatory cycles and to 63.8% of the amount of patients. Multiple pregnancy incidence was 10.4%, and the gestational loses rate was 26%; these results are similar to what has been reported in literature. It is concluded that this medication is a good option of treatment for this type of patients, provided that there are the necessary means to expert and adequate surveillance.
Subject(s)
Hypothalamo-Hypophyseal System/physiopathology , Menotropins/administration & dosage , Ovarian Hyperstimulation Syndrome/chemically induced , Ovulation Induction/methods , Adult , Dose-Response Relationship, Drug , Female , Follow-Up Studies , Humans , Hypothalamo-Hypophyseal System/drug effects , Menotropins/pharmacology , Pregnancy , Treatment Outcome , World Health OrganizationABSTRACT
Fifty couples with unexplainable sterility, were selected for study. They were treated following a uniform treatment protocol, consisting in inducin superovulation by human menopausic gonadotropins hormones, followed by intrauterine insemination with husband's fresh semen. One hundred and thirty six cycles of treatment, were obtained; 15 pregnancies were achieved, corresponding to 30% of the total of couples, and to 11% of amount of treatment cycles. These figures were similar to other author's, and similar to the ones obtained by intrauterine gametes transference. It is concluded that this a new alternative of treatment that may be used before IGT, or in places where there is not such methodology.
