Vestibular dysfunction in adolescents and young adults after kidney transplant.

INTRODUCTION: Chronic kidney disease is a slowly progressive disease that causes irreversible loss of renal function and is considered a public health problem worldwide. OBJECTIVE: To evaluate the vestibular behavior in patients with chronic kidney disease undergoing renal transplantation. METHODS: A retrospective cross-sectional study was performed. Thirty patients were evaluated, 33.3% female and 66.7% male (mean age 16.9 (± 3.6) years old). Patients underwent the following procedures: anamnesis, ENT (ear, nose, and throat) evaluation and vestibular evaluation. RESULTS: The patients reported dizziness when they were on dialysis. 50% the patients showed an abnormality in the vestibular test, which occurred in the caloric test. The abnormality was more prevalent in the peripheral vestibular system and there was a predominance of deficit peripheral vestibular disorders. CONCLUSION: The dizziness was the most significant symptom for the vestibular test in correlation with neurotological symptoms. Alteration in the vestibular exam occurred in the caloric test, there was a prevalence of alterations for the peripheral vestibular system with a predominance of deficit vestibular dysfunction. We emphasize the need to show professionals involved in patients with chronic kidney disease, those undergoing renal transplant and dialitic treatment the importance of prevention and early identification of otoneurological involvement.

Vestibular findings in autosomal recessive ataxia.

OBJECTIVE: This study aims to examine vestibular disorders in patients with recessive spinocerebellar ataxia. DESIGN: A retrospective cross-sectional study was conducted. The patients underwent the following procedures: case history, ENT and vestibular evaluations. STUDY SAMPLE: The tests were performed in 19 patients ranging from 6 to 63 years of age (mean age of 36.7). RESULTS: Clinically, the patients commonly had symptoms of dizziness (57.8%), lack of coordination of movement with imbalance when walking (52.6%), and headaches (42.1%). In vestibular testing, alterations were predominantly evident under caloric testing (73.5%), rotational chair testing, and testing for gaze and optokinetic nystagmus (36.8%). The presence of alterations occurred under examination in 89.5% of these patients, 100% occurred in subjects with Friedreich's ataxia and 84.6% for subjects with indeterminate recessive spinocerebellar ataxia, with the majority occurring in those with central vestibular dysfunction, 57.9% of the examinations. CONCLUSION: The most evident neurotological symptoms were dizziness, lack of coordination of movement, and imbalance when walking. Alterations in vestibular examinations occurred in 89.5% of patients, mostly in the caloric test, with a predominance of deficient central vestibular system dysfunction. This underscores the importance of the contribution of topodiagnostic labyrinthine evaluations for neurodegenerative diseases.