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J Infect Dev Ctries ; 9(4): 431-4, 2015 Apr 15.
Article in English | MEDLINE | ID: mdl-25881536

ABSTRACT

Aspergillosis is an opportunistic fungal infection that may develop in immunocompromised patients with conditions such as leukemia or aplastic anemia. A rare case of stomach perforation following acute fungal gastritis in a 13-year-old female patient with aplastic anemia is reported herein. The patient had developed aplastic anemia without bone marrow fibrosis secondary to acute lymphoblastic leukemia and chemotherapy. The pathological examination revealed a large ischemic transmural perforation (9.5 × 9 cm) associated with fungal septic emboli. Fungal hyphae characteristics were compatible with those of Aspergillus spp. There are few reports identifying fungi as agents associated with gastric perforation. There is a need for early identification of the infectious agent.


Subject(s)
Aspergillosis/complications , Aspergillosis/diagnosis , Aspergillus/isolation & purification , Stomach Diseases/diagnosis , Stomach Diseases/etiology , Adolescent , Anemia, Aplastic/complications , Antineoplastic Agents/therapeutic use , Female , Gastric Mucosa/pathology , Histocytochemistry , Humans , Immunocompromised Host , Microscopy , Pediatrics , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications , Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Stomach Diseases/pathology
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