[Lymphocyte subpopulations and the soluble interleukin-2 receptor in Hashimoto's thyroiditis and subacute thyroiditis]. / Studio delle sottopopolazioni linfocitarie e del recettore solubile dell'interleuchina-2 nella tiroidite di Hashimoto e nella tiroidite subacuta.

There are no univocal experimental data in literature about T cell clone alterations in the peripheral blood during Hashimoto's thyroiditis (TH), autoimmune disease, and during subacute thyroiditis (TSA), an inflammatory thyroid lesion with possibility of "self-perpetuation". The object of our research was to examine the T cell clones, soluble fraction of interleukin 2 receptor and HLA-DR modifications in patients with TH and TSA compared with healthy population. Our results show significant increase of sIL-2r in the TSA compared with normal subjects and with patients TH, where on the contrary, a constant increase of HLA-DR was observed.

[Changes in the thyroid function during treatment of psychiatric disorders using lithium salts]. / Alterazioni della funzionalità tiroidea durante il trattamento di disturbi psichiatrici con sale di litio.

Lithium, a monovalent cation used mainly in the management of certain psychiatric disorders, appears to act on thyroid function and to interfere with T3 and T4 secretion. The authors have followed 10 patients treated with lithium salts for two years and have monitored some parameters of thyroid function. Clinical and laboratory signs of hypothyroidism appeared in one case and subsided after withdrawal of lithium treatment.

[Immunologic and cytologic aspects of Hashimoto's thyroiditis during therapy with thymopentin]. / Aspetti immunologici e citologici della tiroidite di Hashimoto in corso di terapia con timopentina.

Hashimoto's thyroiditis is an autoimmune disease characterized by the presence of thyroid autoantibodies and frequent coexistence of other autoimmune disorders. The object of our research was to examine the peripheral blood and fine-needle cytology modifications in patients with this disease during therapy with Timopentina. Our results suggested a possible therapeutic effect of Timopentina, as an alternative to traditional cortisone treatment.

Diffuse idiopathic skeletal hyperostosis and situs viscerum inversus.

We describe a 74-year-old woman with diffuse idiopathic skeletal hyperostosis (DISH) and situs viscerum inversus. The radiographic alterations typical of DISH were present only on the left side of her thoracic spine. The role of the thoracic aorta in preventing DISH adjacent to its side and some pathogenetic aspects of this skeletal disorder are discussed.

[Clinical and statistical study of 121 cases of acute myocardial infarct from 1976 to 1981 (month of April). Critical review]. / Studio clinico-statistico su 121 casi di infarto miocardico acuto (IMA) dal 1976 al 1981 (mese di aprile). Revisione critica.

The authors realized a retrospective clinical-statistical study about 121 cases of acute myocardial infarction (AMI), treated in the Department of general medicine with a pharmacological association of Lysine acetylsalicylate--Erythrityl tetranitrate--Papaverine hydrochloride, with the purpose of obtaining a vasodilatation on coronary arteries and a platelet antiaggregation, in the light of the new etiopathogenetic views about the prolonged coronary spasm and the platelet aggregation, in some cases of myocardial infarction with or without thrombosis. Obtained data are very optimistic about incidence of left ventricular insufficiency and (of) thromboembolisms, to they augur the sistematic adoption of this treatment of AMI, especially as to the early antiaggregation therapy.