ABSTRACT
The analysis of the nucleoprotein gene of 77 Puumala hantavirus strains detected in human samples in France during 2012-2016 showed that all belonged to the Central European lineage. We observed 2 main clusters, geographically structured; one included strains with the Q64 signature and the other strains with the R64 signature.
Subject(s)
Arvicolinae/virology , Hantavirus Infections/virology , Orthohantavirus/genetics , Puumala virus/genetics , Animals , Cluster Analysis , France/epidemiology , Genomics , Genotype , Geography , Orthohantavirus/isolation & purification , Hantavirus Infections/epidemiology , Humans , Phylogeny , Puumala virus/isolation & purification , ZoonosesABSTRACT
We report detection of Seoul virus in 3 patients in France over a 2-year period. These patients accounted for 3 of the 4 Seoul virus infections among 434 hantavirus infections (1.7%) reported during this time. More attention should be given to this virus in Europe where surveillance has been focused mostly on Puumala and Dobrava-Belgrade hantaviruses.
Subject(s)
Hemorrhagic Fever with Renal Syndrome/diagnosis , Hemorrhagic Fever with Renal Syndrome/epidemiology , Seoul virus , Adult , Animals , Antibodies, Viral , France/epidemiology , Hemorrhagic Fever with Renal Syndrome/virology , Humans , Male , Rats , Young AdultABSTRACT
We report an infection with Tula virus in June 2015, leading to hospitalisation, in a patient living approximately 60 km east of Paris with no previous remarkable medical history. Clinical symptoms were limited to a fever syndrome with severe headache. The main laboratory findings included thrombocytopenia and elevated transaminase levels. Based on S (small) gene sequence analysis, the strain affecting the patient was closely related to strains detected in Central Europe, especially to a south-east German strain.
