Compelled attention: the effects of viewing trauma-related stimuli on concurrent task performance in posttraumatic stress disorder.

We examined the ability of Vietnam veterans with PTSD to focus attention on a primary digit detection task while concurrently viewing neutral or Vietnam-related picture and word distractors. Controlling for combat exposure, military service, and psychopathology, veterans with PTSD took longer to detect the target when Vietnam-related pictures were distractors. There were no reaction time differences when word stimuli were distractors. The latency effect was specific to trials with trauma-related pictures and did not spread to neutral trials interleaved within a mixed block of trauma and neutral pictures. Individuals with PTSD recalled proportionally more Vietnam-related words than other groups, implying differential attention to Vietnam-related words. Attending to trauma-related pictures interferes with performance of a concurrent task by individuals with PTSD.

Twenty-four-hour ambulatory blood pressure and heart rate monitoring in combat-related posttraumatic stress disorder.

This study examined the cardiovascular correlates of posttraumatic stress disorder (PTSD) in Vietnam combat veterans using 24-hr ambulatory blood pressure and heart rate monitoring. Veterans with PTSD (n = 11) exhibited significantly higher heart rate and diastolic blood pressure across the 24 hr than veterans without PTSD (n = 7) (80.8 vs. 71.9 bpm, and 80.1 vs. 71.5 mm Hg, respectively). Heart rate during sleep was also significantly higher among veterans with PTSD, compared to veterans without PTSD (71.0 vs. 62.7 bpm). These results, based on a more naturalistic measurement methodology used outside the laboratory, support an association between PTSD and increased chronic cardiovascular arousal.

Eye movement desensitization and reprocessing (EDMR) treatment for combat-related posttraumatic stress disorder.

Despite the clinical and social impact of posttraumatic stress disorder (PTSD), there are few controlled studies investigating its treatment. In this investigation, the effectiveness of two psychotherapeutic interventions for PTSD were compared using a randomized controlled outcome group design. Thirty five combat veterans diagnosed with combat-related PTSD were treated with either (a) 12 sessions of eye movement desensitization and reprocessing, EMDR (n = 10), (b) 12 sessions of biofeedback-assisted relaxation (n = 13), or (c) routine clinical care, serving as a control (n = 12). Compared with the other conditions, significant treatment effects in the EMDR condition were obtained at posttreatment on a number of self-report, psychometric, and standardized interview measures. Relative to the other treatment group, these effects were generally maintained at 3-month follow-up. Psychophysiological measures reflected an apparent habituation effect from pretreatment to posttreatment but were not differentially affected by treatment condition.

The Honolulu posttraumatic stress disorder stimulus set.

We present word and picture stimuli constituting a validated stimulus set appropriate for cognitive investigations of posttraumatic stress disorder (PTSD). Combat related and neutral words and pictures were rated by Vietnam veterans with PTSD and by three comparison groups along four dimensions: unpleasantness, Vietnam relevance, stressfulness, and memorability. There were distinctive patterns of responses by the PTSD group which efficiently discriminated the individuals in this group from those in the control groups. These stimuli have the potential to be developed as a diagnostic instrument.

Facial EMG responses to combat-related visual stimuli in veterans with and without posttraumatic stress disorder.

Veterans with (n = 10) and without (n = 10) posttraumatic stress disorder (PTSD) participated in an exploratory study of facial reactivity to neutral slides and to slides depicting unpleasant combat-related material that were previously determined to be emotionally evocative. It was found that the zygomaticus major (cheek), masseter (jaw), and lateral frontalis (forehead) muscles were especially reactive to the combat slides in the veterans with PTSD, suggesting the importance of facial emotional expression in this disorder. The PTSD participants' self-reports of overall distress paralleled these effects. However, autonomic reactivity did not reflect general arousal effects due to the visual stimuli, showing both the sensitivity of facial muscle assessment in this context and the need for further research on the relationship between stimulus modality and physiological trauma reactions. Additional directions for research in this area are discussed including efforts to correlate subjective and physiological reactions.

Characteristics of veterans in Hawaii with and without diagnoses of post-traumatic stress disorder.

A total of 118 combat veterans seeking services at the VA Medical Center in Honolulu were assessed on a variety of demographic and psychometric dimensions, permitting the first systematic comparison on the measured variables between veterans with and without PTSD in the multicultural population of veterans in Hawaii. The results have implications for medical interventions with this population.

Conditioning of skin conductance levels through a combined instrumental-classical conditioning procedure.

A paucity of studies and inconsistent results characterize attempts to instrumentally condition tonic electrodermal activity. The present study was conducted to further explore the classical and instrumental conditioning of skin conductance levels (SCLs) through auditory analogue feedback. Fifty undergraduates were randomly assigned to one of five groups of equal size: instrumental conditioning alone, classical conditioning alone, instrumental and classical conditioning combined, and two control groups. The combined training group achieved significantly higher SCLs relative to the group receiving instrumental conditioning alone.

Chinese hamster ovary cell mitosis and its response to ionizing radiation: a morphological analysis of the living cell.

Repeated microscopic observations of exponentially growing Chinese hamster ovary cells were made and the times and mitotic stages were recorded in control and irradiated cultures at 37 degrees C. As determined by autoradiography, the time from the end of S phase to early prophase (the G2 phase) was 46 min, to breakdown of the nuclear envelope was 91 min, and to restoration of the nuclear envelope was 116 min. The time spent in morphologically distinguishable phases of mitosis and the effects of 0.5, 1.0, 1.5, 2.0, and 4.0 Gy of gamma or X radiation on cells at each phase were determined. Affected cells were found to be delayed without or with reversion to an earlier mitotic stage before recovering and advancing through mitosis. Cells were timed in the five steps comprising delay with reversion: inertia, cessation I, regression, cessation II, and reprogression. No cells treated in late prophase, i.e., within 8-10 min of nuclear envelope breakdown, were delayed by the doses used; therefore the critical or transition point must be situated in middle prophase. Cells irradiated in this stage were not delayed by 0.5 or 1.0 Gy, but suffered a dose-dependent delay with or without reversion after 1.5, 2.0, and 4.0 Gy. Cells irradiated in early prophase and very late interphase responded similarly, but a greater percentage of the latter reverted.

Intercellular bridges and factors determining their patterns in the grasshopper testis.

Intercellular bridges joining cells contained in cysts of Chortophaga viridifasciata testes were studied with light and electron microscopy. Preparations consisted of expressed whole cells (living, or fixed and stained) as well as sections. The secondary spermatogonia of each cyst are joined centrally by persisting fused interzonal bodies (fusomes) of incompletely cleaved cells. Shifts in cell orientation during anaphase are apparently responsible for central as opposed to chain linkage of cells. In the primary spermatocytes, the central fusome is replaced by a chain linkage, apparently resulting from the breakdown of the fusome into its original interzonal body components. Intercellular bridges are also present in spermatids, but there is no evidence to indicate the time of their formation (in the immediately preceding meiotic divisions or in the secondary spermatogonial divisions). The function of the compact centrally situated fusome in the secondary spermatogonial cyst is discussed as it relates to synchrony, number of cell divisions, spermatodesm formation, and fertility.

The behavioral treatment of Raynaud's disease: a review.

Raynaud's disease is a peripheral vascular system disorder characterized by episodes of vasoconstriction in the hands and feet resulting in a lowering of skin temperature and pain. Recent studies are reviewed that focus on the behavioral treatment of Raynaud's disease--in particular, biofeedback and autogenic training. Methodological problems and other difficulties include the measurement of skin temperature, schedules of reinforcement/feedback, and characteristics of the experimenter and subject. Studies in this area indicate some promise for certain behavioral interventions, especially finger temperature biofeedback under cold stress conditions. On the other hand, further research is needed to clarify the mechanisms, especially that of vasodilation, and the applications of temperature biofeedback, as well as the role of attitudinal, interpersonal, and cognitive factors.

The health compliance model.

Another model for integrating a wide diversity of evidence related to compliance is proposed, termed the Health Compliance (HC) model. The HC model incorporates situational-antecedent, consequence, and organismic factors, including cognitive processes, as they relate functionally to compliance behaviors. A selective review of the compliance literature suggests the scope and organizational possibilities of the model.

Recent assessments of the Myers-Briggs Type Indicator.

The present paper focuses on approximately two dozen recent published studies that examined reliability and validity of the Myers-Briggs Type Indicator (MBTI) in clinical, counseling, and research settings. Several assessments of split-half and test-retest reliability of the standard Form F and shorter Form G of the Inventory have yielded generally satisfactory correlations for all four scales. A larger number of studies of construct validity of the MBTI have yielded support for research hypotheses in situations ranging from correlations of the MBTI with a personality inventory, to couples problems in a counseling setting, to line judgment in groups, and others. Therefore, the applications of the MBTI have been broad, although somewhat unsystematic, and with generally favorable validity assessment. Continued attempts to validate the instrument in a variety of settings are needed.

Single- and successive-site EMG training in responding to anticipated pain.

In a comparison among relaxation procedures, 32 college students were assigned to four group of equal size. Electromyographic response training was given with biofeedback (EMG training) on the forehead (frontal area) alone, on the frontal area, neck (sternomastoid), and forearm areas in succession, or on these three sites in conjunction with recorded relaxation instructions used at home. Relative to a control group, which received no training, the three biofeedback-trained groups maintained lower EMG levels on the frontal and sternomastoid sites, and the group provided with the relaxation instructions plus EMG training showed lower skin conductance levels. These patterns were generally maintained during the presentation of a stimulus (stressor) that ostensibly signaled an impending electric shock. Other measures, including peripheral temperatures and self-reported anxiety, also showed effects consistent with the stressor presentations but did not differentiate the groups. The results are discussed in terms of common clinical relaxation procedures, an alternative procedure for training several sites simultaneously, and implications for models of EMG training and arousal.

Expectancies of reinforcement control in biofeedback and cognitive performance.

This study investigated the effects of expectancies concerning the controllability of outcomes in a biofeedback task. Forty-eight college undergraduates were subjects. Frontal (forehead) electromyographic (EMG) responses were measured during baseline (no treatment), pretreatment, and test sessions. During pretreatment, subjects were assigned to one of three groups. Using a fictitious blood vessel control task, the success group received false feedback and instructions that conveyed that outcomes had been successfully controlled. The failure group received feedback and instructions that conveyed that outcomes had not been controlled. A control group was given no specific task. During the subsequent test stage, all subjects were asked to reduce frontal muscle tension levels through relaxation while assisted with true EMG feedback. Relative to the success and control groups. EMG levels of the failure group reflected more rapid acquisition of frontal muscle relaxation. However, performance on a cognitive task was not affected by the pretreatment. It was concluded that expectancies generated during the false feedback pretreatment were related to later biofeedback performance. The results were discussed in terms of concepts of locus of control and theories of learned helplessness and reactance.

Role of incentives in the training of the frontal EMG relaxation response.

Male college students were assigned to a feedback condition in which an auditory signal was correlated with forehead electromyographic (EMG) responses or to a control condition in which a constant low tone was provided. Within each condition, half of the subjects were provided with an incentive for successful reductions of EMG levels from session to session. In the control condition incentives were actually given on the basis of performance of yoked feedback partners. The remaining subjects in each condition (no incentive) were instructed that the incentive was available for reliable participation in the experiment. Feedback subjects acquired lower EMG levels than control subjects, and the yoked-incentive subjects acquired lower levels than no-incentive subjects in the control condition. There were no major differences in EMG levels attributable to locus of control orientation. The results are discussed mainly in terms of implications of incentive variables for reinforcement analyses of biofeedback effects and the validity of the locus of control construct in this application.