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J Comp Physiol Psychol ; 92(2): 280-8, 1978 Apr.
Article in English | MEDLINE | ID: mdl-566771

ABSTRACT

Offspring of rats infected daily from Day 16 through Day 20 of gestation with either 2 mg of testosterone propionate (TP) in .1 ml of sesame oil or oil alone were tested for sexual receptivity following injections of 3.3 microgram of estradiol benzoate (EB) and .5 mg of progesterone (P) beginning at 40, 80, or 120 days of age. At each age, neonatally gonadectomized males and females from TP-injected litters exhibited less receptivity than corresponding oil-injected controls. Prenatally androgenized females were similar to neonatally castrated oil-injected males at all ages. Ovarian implants from birth to 35 days of age significantly increased receptivity in neonatally castrated males and androgenized females. Increasing the age at which testing was initiated systematically reduced receptivity in all groups.


Subject(s)
Animals, Newborn/growth & development , Estradiol/pharmacology , Maternal-Fetal Exchange , Progesterone/pharmacology , Sexual Behavior, Animal/drug effects , Testosterone/pharmacology , Age Factors , Animals , Castration , Female , Gestational Age , Male , Ovary/transplantation , Pregnancy , Rats , Sex Factors , Transplantation, Homologous
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