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1.
Soc Psychiatry Psychiatr Epidemiol ; 47(7): 1077-86, 2012 Jul.
Article in English | MEDLINE | ID: mdl-21739224

ABSTRACT

PURPOSE: Deficits in social functioning are a core feature of schizophrenia and are influenced by both symptomatic and neurocognitive variables. In the present study we aimed to determine the reliability and validity of the Portuguese version of the Personal and Social Performance (PSP) scale, and possible correlations with measures of cognitive functioning. METHODS: One-hundred and four community and inpatients with schizophrenia were assessed using measures of social functioning and symptom severity alongside measures of executive function, processing speed, and verbal memory. RESULTS: Convergent validity with the GAF in the four domains of the PSP varied from 0.357 to 0.899. Reliability was found to be satisfactory, with a Cronbach's alpha coefficient of 0.789. Inter-rater reliability in the four domains of the PSP varied from 0.430 to 0.954. Low-functioning patients (PSP < 70) were older, had longer duration of illness, were more symptomatic and had worse cognitive performances, as compared with high-functioning patients (PSP ≥ 70). In a regression model, deficits in social functioning were strongly predicted both by symptomatic and neurocognitive variables; these together accounted for up to 62% of the variance. CONCLUSIONS: The present study supports the reliability and validity of the Portuguese language version of the PSP and further supports the original measure. The co-administration of brief cognitive assessments with measures of functioning may lead to more focused interventions, possibly improving outcomes in this group.


Subject(s)
Cognition , Hospitalization , Interpersonal Relations , Language , Psychiatric Status Rating Scales/standards , Schizophrenia/physiopathology , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Portugal , Psychometrics , Schizophrenia/diagnosis , Severity of Illness Index , Young Adult
2.
Acta Med Port ; 24(5): 739-56, 2011.
Article in Portuguese | MEDLINE | ID: mdl-22525626

ABSTRACT

Club drugs are the following substances: Methylenedioxymethamphetamine (MDMA); Methamphetamine; Lysergic Acid Diethylamide (LSD); Ketamine; Gamma-hydroxybutyrate (GHB) and Flunitrazepam. These substances are mainly used by adolescents and young adults, mostly in recreational settings like dance clubs and rave parties. These drugs have diverse psychotropic effects, are associated with several degrees of toxicity, dependence and long term adverse effects. Some have been used for several decades, while others are relatively recent substances of abuse. They have distinct pharmacodynamic and pharmacokinetic properties, are not easy to detect and, many times, the use of club drugs is under diagnosed. Although the use of these drugs is increasingly common, few health professionals feel comfortable with the diagnosis and treatment. The authors performed a systematic literature review, with the goal of synthesising the existing knowledge about club drugs, namely epidemiology, mechanism of action, detection, adverse reactions and treatment. The purpose of this article is creating in Portuguese language a knowledge data base on club drugs, that health professionals of various specialties can use as a reference when dealing with individual with this kind of drug abuse.


Subject(s)
Illicit Drugs , Substance-Related Disorders , Adolescent , Flunitrazepam/adverse effects , Flunitrazepam/pharmacology , Humans , Illicit Drugs/adverse effects , Illicit Drugs/pharmacology , Ketamine/adverse effects , Ketamine/pharmacology , Lysergic Acid Diethylamide/adverse effects , Lysergic Acid Diethylamide/pharmacology , Methamphetamine/adverse effects , Methamphetamine/pharmacology , N-Methyl-3,4-methylenedioxyamphetamine/adverse effects , N-Methyl-3,4-methylenedioxyamphetamine/pharmacology , Sodium Oxybate/adverse effects , Sodium Oxybate/pharmacology , Substance-Related Disorders/diagnosis , Substance-Related Disorders/therapy , Young Adult
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