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1.
Eur Rev Med Pharmacol Sci ; 27(18): 8895-8904, 2023 Sep.
Article in English | MEDLINE | ID: mdl-37782198

ABSTRACT

OBJECTIVE: Endometrial polyps (EPs) are one of the most common pathologies detected during the examination of the uterine cavity of infertile women. We aimed to demonstrate the relationship between EPs, chronic endometritis (CE) and in vitro fertilization (IVF) outcomes. PATIENTS AND METHODS: This retrospective study was performed on 394 hysteroscopically examined infertility cases. We performed polyp resections (PR) and extensive biopsies of the endometrium to demonstrate the association with clinical pregnancy (CP) by IVF. We performed statistical analysis to compare these associations. RESULTS: The incidence of CE was twice as high in the presence of EPs as in the absence of EPs. The associations between EPs and PR were found to be significant for positive CP outcomes. A significant difference in IVF outcome was found between the group with EPs and the group without EPs. All these associations were statistically significant (p < 0.05). CONCLUSIONS: We found a frequent association between EPs and CE. The pregnancy rate obtained after IVF was negatively affected by the presence of EPs. Treatment of these pathologies improved IVF outcomes.


Subject(s)
Endometritis , Infertility, Female , Polyps , Pregnancy , Female , Humans , Endometritis/epidemiology , Endometritis/complications , Endometritis/pathology , Infertility, Female/therapy , Retrospective Studies , Hysteroscopy , Endometrium/pathology , Fertilization in Vitro/adverse effects , Chronic Disease , Polyps/epidemiology , Polyps/complications , Polyps/pathology
2.
Eur Rev Med Pharmacol Sci ; 27(12): 5575-5582, 2023 06.
Article in English | MEDLINE | ID: mdl-37401294

ABSTRACT

OBJECTIVE: To preserve ovarian reserve, we treated ovarian endometriomas by ultrasound-guided aspiration followed by sclerotherapy of the cyst mucosa. We compared the results with laparoscopic cystectomy. PATIENTS AND METHODS: We conducted a retrospective study of 96 women with ovarian endometriomas. In 54 of the women, ultrasound-guided aspiration of the contents was performed, followed by chemical sclerotherapy of the cyst plaque with ethanol. Laparoscopic cystectomy was performed in the remaining 42 women. RESULTS: Statistical analysis of anti-Mullerian hormone (AMH) levels before and after the procedures showed a significant decrease in the case of cystectomy compared with ethanolic ovarian sclerotherapy (EOS). CONCLUSIONS: Conservative treatment by echo-assisted puncture and sclerotherapy with ethanol proved to be a viable treatment for the removal of ovarian endometriomas. It is a simple procedure that does not affect ovarian reserve or fertility.


Subject(s)
Cysts , Endometriosis , Laparoscopy , Ovarian Cysts , Ovarian Reserve , Female , Humans , Endometriosis/surgery , Sclerotherapy , Retrospective Studies , Laparoscopy/methods , Ethanol/therapeutic use , Ovarian Cysts/surgery
3.
Eur Rev Med Pharmacol Sci ; 26(16): 5932-5938, 2022 08.
Article in English | MEDLINE | ID: mdl-36066169

ABSTRACT

INTRODUCTION: We report a case of successful pregnancy after in vitro fertilization culture (IVF) medium contaminated with Escherichia coli (E. coli). CASE REPORT: To remove E. coli, oocytes were isolated in a PVP-ICSI medium and then in a culture medium supplemented with gentamicin. We selected two embryos that were vitrified and frozen. In the next natural cycle, we performed the embryo transfer of 2 embryos. RESULTS: Only one pregnancy was uncomplicated until term and was completed by the live birth of a healthy baby. The child's subsequent development until the date of publication of this article is normal. CONCLUSIONS: In cases of E. coli contamination of the IVF culture medium, specific laboratory methods allow the procedure to be continued, and a healthy baby can be obtained.


Subject(s)
Embryo Transfer , Escherichia coli , Embryo Transfer/methods , Female , Fertilization in Vitro/methods , Humans , Live Birth , Oocytes , Pregnancy , Pregnancy Rate
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