ABSTRACT
INTRODUCTION: Paratesticular tumors are rare. Most of them are benign, and adenomatoid tumors are most common. These tumors sometimes infiltrate the testicular parenchyma and require differential diagnosis with malignant tumors. In such cases, intraoperative biopsy allows for performing conservative surgery. MATERIALS AND METHODS: A retrospective study of nine patients with paratesticular adenomatoid tumors seen during a nine-year period (2000-2008) is reported. RESULTS AND CONCLUSIONS: Patient age (mean, 49.6 years) and most common initial signs (tender nodule) are reported. The tumor most commonly occurred as a small, usually oval, nodule in the tail of epididymis. Our series included a case each of intraparenchymal tumor of the testis and tumor of the tunica vaginalis. Diagnosis was initially made based on a ultrasound scan and subsequently confirmed by histology. Differential diagnosis and surgical treatment, performed in all patients, are reported, and also the pathological features of surgical specimens.
Subject(s)
Adenomatoid Tumor/pathology , Epididymis/pathology , Genital Neoplasms, Male/pathology , Adenomatoid Tumor/chemistry , Adenomatoid Tumor/diagnostic imaging , Adenomatoid Tumor/surgery , Adult , Calbindin 2 , Diagnosis, Differential , Epididymis/surgery , Genital Neoplasms, Male/chemistry , Genital Neoplasms, Male/diagnostic imaging , Genital Neoplasms, Male/surgery , Humans , Keratins/analysis , Male , Middle Aged , Neoplasm Invasiveness , Neoplasm Proteins/analysis , Retrospective Studies , S100 Calcium Binding Protein G/analysis , Testis/pathology , UltrasonographyABSTRACT
Lipomas are common benign neoplasms affecting many adipose tissue-containing organs of the body, including bone. Central lesions in bone account for less than 1% of all lipomas. In the literature, intraosseous lipomas have been reported in various bones such as the frontal and parietal bones, ribs, ulna, phalanges of hand and foot, femoral neck, fibula and calcaneum. No preference has been described for gender or race. As far as the authors know, there have been no documented cases of intraosseous lipoma involving the temporomandibular joint. This report describes a rare case of mandibular intraosseous lipoma in the left condylar area associated with temporomandibular dysfunction.
Subject(s)
Lipoma/pathology , Mandibular Condyle/pathology , Mandibular Neoplasms/pathology , Temporomandibular Joint Disorders/pathology , Female , Humans , Middle AgedABSTRACT
Introducción: los tumores paratesticulares son raros. La mayoría son benignos, siendo el más frecuente el tumor adenomatoide. En ocasiones estos tumores infiltran el parénquima testicular y es necesario plantear un diagnóstico diferencial con tumores malignos, por lo que la biopsia intraoperatoria, en estos casos, permite realizar una cirugía conservadora. Material y métodos: presentamos de forma retrospectiva nuestra extraordinaria serie de 9 casos de tumores adenomatoides paratesticulares durante un periodo de 9 años (2000- 2008). Resultados y conclusiones: describimos la edad de los pacientes (media de 49,6 años) y la clínica de inicio (nódulo palpable doloroso). La localización de la lesión más frecuente fue en el epidídimo, que habitualmente se manifiesta como un nódulo de pequeño tamaño, generalmente oval en la cola del epidídimo. En nuestra serie tenemos un caso de lesión testicular intraparenquimatosa y otro en túnica vaginal; el resto se localizan en el epidídimo. El diagnóstico de sospecha fue por ecografía, con confirmación histológica posterior. Describimos el diagnóstico diferencial y el tratamiento quirúrgico, que se aplicó en el 100% de los casos, así como sus características anatomopatológicas(AU)
Introduction: Paratesticular tumors are rare. Most of them are benign, and adenomatoid tumors are most common. These tumors sometimes infiltrate the testicular parenchyma and require differential diagnosis with malignant tumors. In such cases, intraoperative biopsy allows for performing conservative surgery. Materials and methods: A retrospective study of nine patients with paratesticular adenomatoid tumors seen during a nine-year period (2000-2008) is reported. Results and conclusions: Patient age (mean, 49.6 years) and most common initial signs (tender nodule) are reported. The tumor most commonly occurred as a small, usually oval, nodule in the tail of epididymis. Our series included a case each of intraparenchymal tumor of the testis and tumor of the tunica vaginalis. Diagnosis was initially made based on a ultrasound scan and subsequently confirmed by histology. Differential diagnosis and surgical treatment, performed in all patients, are reported, and also the pathological features of surgical specimens(AU)
Subject(s)
Humans , Male , Adenomatoid Tumor/complications , Adenomatoid Tumor/diagnosis , Adenomatoid Tumor/surgery , Diagnosis, Differential , Adenomatoid Tumor/physiopathology , Adenomatoid Tumor , Epididymis/pathology , Epididymis/surgery , Epididymis , Retrospective Studies , Keratins , Keratins/ultrastructureABSTRACT
Chromophobe renal cell carcinoma (CRCC) is a rare variant of renal carcinomas arising from the intercalated cells of the distal renal tubule and representing 5% among all renal tumors. Its biological behaviour is variable, less aggresive than clear cell renal carcinoma. Histochemical, ultrastructural and molecular genetic characteristics are different from other renal carcinomas. Age at presentation is about the 6th decade of life. We report an exceptional 10 year-old boy case with a CRCC. Diagnostic and therapeutic aspects for the management of this tumor are reviewed.
Subject(s)
Carcinoma, Renal Cell , Kidney Neoplasms , Carcinoma, Renal Cell/diagnosis , Carcinoma, Renal Cell/surgery , Child , Humans , Kidney Neoplasms/diagnosis , Kidney Neoplasms/surgery , MaleABSTRACT
El carcinoma renal de células cromófobas (CRCC) es una variante rara de carcinoma renal que se origina de las células intercaladas del epitelio tubular distal y constituye un 5% de los tumores renales. Es un tumor de comportamiento biológico variable, menos agresivo que el carcinoma convencional de células claras. Presenta características histoquímicas, ultra estructurales y genéticas diferentes al resto de carcinomas renales. La edad de presentación suele ser hacia la 6ª década de vida. Presentamos un caso excepcional de CRCC en un niño de 10 años de edad. Se revisan los aspectos diagnósticos y terapéuticos del manejo de este tumor (AU)
Chromophobe renal cell carcinoma (CRCC) is a rare variant of renal carcinomas arising from the intercalated cells of the distal renal tubule and representing 5% among all renal tumors. Its biological behaviouris variable, less aggresive than clear cell renal carcinoma. Histochemical, ultrastructural and molecular genetic characteristics are different from other renal carcinomas. Age at presentation is about the 6th decade of life. We report an exceptional 10 year-old boy case with a CRCC. Diagnostic and therapeutic aspects for the management of this tumor are reviewed (AU)
Subject(s)
Humans , Male , Child , Carcinoma, Renal Cell/diagnosis , Carcinoma, Renal Cell/surgery , Kidney Neoplasms/diagnosis , Kidney Neoplasms/surgery , Carcinoma, Renal Cell/pathology , Kidney Neoplasms/pathology , NephrectomyABSTRACT
La esclerosis tuberosa es una anomalía congénita del desarrolloembrionario que se transmite de forma autosómica dominante caracterizadapor la presencia por trastornos neurológicos, cutáneos o dermatológicos,y retraso mental. Se pueden afectar otros órganos y sistemas, ydar manifestaciones orofaciales. La lesión a nivel del esmalte dental constituyela lesión intraoral más frecuente. Rara vez se pueden encontrar lesionesóseas en los maxilares. El fibroma desmoplásico es un infrecuente tumorfibroso intraóseo localmente agresivo de lento crecimiento, que se asociamuy rara vez a la esclerosis tuberosa. Presentamos el caso clínico de unpaciente de 33 años afecto de esclerosis tuberosa con una lesión en la mandíbuladiagnosticada como fibroma desmoplásico. Se discuten los métodosdiagnósticos, presentación clínica y tratamiento(AU)
Tuberous sclerosis is a congenital anomaly of embryonicdevelopment with an autosomal dominant inheritance. It ischaracterized by the presence of neurologic and dermatologicdisorders and mental retardation. It can affect other organs andsystems and produce orofacial manifestations. Dental enamel defectsare the most frequent intraoral lesion. Bone lesions rarely occur inthe upper jaw. Desmoplastic fibroma is an infrequent, slow-growing,locally aggressive intraosseous fibrous tumor that rarely is associatedwith tuberous sclerosis. We report the clinical case of a 33-year-oldman with tuberous sclerosis and a jaw lesion diagnosed asdesmoplastic fibroma. The diagnostic methods, clinical presentation,and treatment are discussed(AU)
Subject(s)
Humans , Male , Adult , Tuberous Sclerosis/complications , Fibroma, Desmoplastic/complications , Mandibular Neoplasms/complications , /analysisABSTRACT
A cementoblastoma is rare, benign, and of odontogenic ectomesenchymal origin, usually associated with the roots of the first mandibular tooth. We present an unusual case of one that involved the roots of the first and second maxillary molars, extended into the maxillary sinus, and was associated with a displaced unerupted third molar. The initial presentation was misleading and resulted in inadequate management. The definitive diagnosis had not been established until 2 years later.
