ABSTRACT
OBJECTIVE: Renal angiomyolipoma is a mesenchymal neoplasm composed of dysmorphic blood vessels, smooth muscle, and adipose tissue. Epithelioidangiomyolipoma is an uncommon variant considered potentially malignant. We report a case of renal epithelioid angiomyolipoma suspicious for urothelialcarcinoma of renal pelvis. METHODS: A 50-year-old woman with a 3-day history of macroscopic hematuria and CT-scan showing a tumor arising from the left renal pelvis suspicious for urothelialcarcinoma. Nephrectomy was analysed in multiple slides of hematoxilin-eosin and immunohistochemistry. RESULTS: Left nephrectomy was performed. Tumor sized 8 cm and showed pathologic findings of epithelioid angiomyolipoma with a little component of classic angiomyolipoma. We studied differential diagnosis and pathologic characteristics for the prognosis. CONCLUSIONS: Pathologic study in detail is fundamental for differential diagnosis and prognosis of this tumor. Our patient's pathology showed good prognosis, however follow-up is important due the malignant potential of the neoplasm.
Subject(s)
Angiomyolipoma/pathology , Carcinoma/pathology , Kidney Neoplasms/pathology , Kidney Pelvis/pathology , Angiomyolipoma/diagnostic imaging , Angiomyolipoma/surgery , Carcinoma/diagnostic imaging , Carcinoma/surgery , Epithelioid Cells/pathology , Female , Humans , Immunohistochemistry , Kidney Neoplasms/diagnostic imaging , Kidney Neoplasms/surgery , Kidney Pelvis/diagnostic imaging , Kidney Pelvis/surgery , Middle Aged , Nephrectomy , Tomography, X-Ray ComputedABSTRACT
OBJETIVO: El angiomiolipoma renal es una neoplasia compuesta de vasos sanguíneos dismórficos, músculo liso y tejido adiposo. El angiomiolipoma epitelioide es una variante rara potencialmente maligna. Aportamos un caso de angiomiolipoma epitelioide renal sospechoso de carcinoma urotelial de pelvis. MÉTODO: Mujer de 50 años con hematuria y masa, en la tomografía axial computerizada, sospechosa de carcinoma urotelial de pelvis renal. Se analiza patológicamente la pieza de nefrectomía, con múltiples cortes histológicos de hematoxilina-eosina y técnicas inmunohistoquímicas. RESULTADOS: Se realiza nefrectomía izquierda. El riñón muestra tumor de 8cm con rasgos morfoinmunohistoquímicos de angiomiolipoma epitelioide, con escaso componente de angiomiolipoma clásico. Planteamos diagnóstico diferencial y analizamos los datos patológicos de pronóstico. CONCLUSIONES: El estudio patológico detallado del tumor es fundamental para el diagnóstico diferencial y su pronóstico. En este caso la paciente no presentaba rasgos indicativos de mal pronóstico, aunque el seguimiento es fundamental dado el potencial maligno de la neoplasia (AU)
OBJECTIVE: Renal angiomyolipoma is a mesenchymal neoplasm composed ofdysmorphic blood vessels, smooth muscle, and adipose tissue. Epithelioidangiomyolipoma is an uncommon variant considered potentially malignant. Wereport a case of renal epithelioid angiomyolipoma suspicious for urothelialcarcinoma of renal pelvis. METHODS: A 50-year-old woman with a 3-day history of macroscopic hematuria and CT-scan showing a tumor arising from the left renal pelvis suspicious for urothelialcarcinoma. Nephrectomy was analysed in multiple slides of hematoxilin-eosinand immunohistochemistry. RESULTS: Left nephrectomy was performed. Tumor sized 8cm and showed pathologic findings of epithelioid angiomyolipoma with a little component of classic angiomyolipoma. We studied differential diagnosis and pathologic characteristics for the prognosis. CONCLUSIONS: Pathologic study in detail is fundamental for differential diagnosisand prognosis of this tumor. Our patient`spathology showed good prognosis, however follow-up is important due the malignant potential of the neoplasm (AU)
