ABSTRACT
CASO CLÍNCO:Mujer de 43 años con leucemia linfoblástica T en remisión completa, remitida por sospecha de necrosis retiniana herpética/retinitis leucémica en el ojo izquierdo (OI). La agudeza visual era de unidad y el fondo de ojo presentaba retinitis y hemorragias en periferia. Ante estudio hematológico negativo, recibió tratamiento por retinitis por citomegalovirus. Tras mejoría inicial, aparece papilitis en el OI y restricción de la motilidad en el ojo derecho. La resonancia y punción lumbar confirman la recidiva leucémica. DISCUSIÓN: La afectación ocular puede preceder a la recaída hematológica, por eso debe sospecharse ante sintomatología ocular. Además, son frecuentes las infecciones oportunistas en inmunodeprimidos
CLINICAL CASE: A 43-year-old woman in remission from T- cell acute lymphoblastic leukaemia was referred to our hospital with suspected leukaemic retinitis. The funduscopic examination of her left eye revealed multifocal yellow-white peripheral retinitis and retinal haemorrhage. The patient was treated for cytomegalovirus retinitis after an extended haematological investigation showed no abnormalities. Initial improvement was followed by papillitis in the left eye and motility restriction in the right eye. Magnetic resonance and lumbar puncture confirmed leukaemia relapse. Specific treatment was initiated with complete resolution. DISCUSSION: Ocular involvement may precede haematological leukaemia relapse. Physicians should be alerted when ocular symptoms appear in these cases
Subject(s)
Humans , Female , Adult , Cytomegalovirus Retinitis/complications , Cytomegalovirus Retinitis/diagnosis , Cytomegalovirus Retinitis/therapy , Papilledema/complications , Papilledema/diagnosis , Optic Nerve , Optic Nerve , Leukemia/complications , Leukemia, Biphenotypic, Acute/complications , Cytomegalovirus Retinitis/drug therapy , Cytomegalovirus Retinitis/radiotherapyABSTRACT
CLINICAL CASE: A 43-year-old woman in remission from T- cell acute lymphoblastic leukaemia was referred to our hospital with suspected leukaemic retinitis. The funduscopic examination of her left eye revealed multifocal yellow-white peripheral retinitis and retinal haemorrhage. The patient was treated for cytomegalovirus retinitis after an extended haematological investigation showed no abnormalities. Initial improvement was followed by papillitis in the left eye and motility restriction in the right eye. Magnetic resonance and lumbar puncture confirmed leukaemia relapse. Specific treatment was initiated with complete resolution. DISCUSSION: Ocular involvement may precede haematological leukaemia relapse. Physicians should be alerted when ocular symptoms appear in these cases.
Subject(s)
Cytomegalovirus Retinitis/etiology , Leukemic Infiltration , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/complications , Retina/pathology , Adult , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Combined Modality Therapy , Cytarabine/administration & dosage , Female , Granulocyte Colony-Stimulating Factor/administration & dosage , Humans , Idarubicin/administration & dosage , Leukemic Infiltration/drug therapy , Leukemic Infiltration/radiotherapy , Papilledema/etiology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/radiotherapy , Recurrence , Retinal Hemorrhage/etiology , Vidarabine/administration & dosage , Vidarabine/analogs & derivativesABSTRACT
CASO CLÍNICO: Paciente de 7 años, varón, diagnosticado de xeroderma pigmentoso (XP), remitido a oftalmología por presencia de múltiples tumoraciones en el ojo izquierdo, que afectan a párpados y conjuntiva. Presenta una tumoración en el párpado inferior, que afecta al borde libre, originando un ectropión secundario y varias lesiones de aspecto melanocítico en conjuntiva. Se realiza resección quirúrgica de la tumoración palpebral y las lesiones conjuntivales colocando un injerto de piel y de membrana amniótica, respectivamente como recubrimiento. DISCUSIÓN: Los pacientes con XP tienen una alta probabilidad de desarrollo tumoraciones oculares. Es necesaria una exploración oftalmológica exhaustiva para establecer un diagnóstico precoz
CLINICAL CASE: Seven-year-old male patient, affected by xeroderma pigmentosum (XP) who was referred to ophthalmology due to the presence of numerous tumours in his left eye that affected the eyelids and conjunctiva. He had a tumour in his lower eyelid that affected the free edge, creating a secondary ectropion, and several lesions with a melanocytic appearance in conjunctiva. A resection of the eyelid tumour and the conjunctival lesions were performed by placing a skin graft and amniotic membrane, respectively, as covering. DISCUSSION: XP patients have high probability of developing eye tumours. A thorough ophthalmic examination is necessary to establish an early diagnosis
Subject(s)
Humans , Male , Child , Eyelid Neoplasms/surgery , Xeroderma Pigmentosum/complications , Plastic Surgery Procedures/methods , Amnion/pathology , Surgical FlapsABSTRACT
CLINICAL CASE: Seven-year-old male patient, affected by xeroderma pigmentosum (XP) who was referred to ophthalmology due to the presence of numerous tumours in his left eye that affected the eyelids and conjunctiva. He had a tumour in his lower eyelid that affected the free edge, creating a secondary ectropion, and several lesions with a melanocytic appearance in conjunctiva. A resection of the eyelid tumour and the conjunctival lesions were performed by placing a skin graft and amniotic membrane, respectively, as covering. DISCUSSION: XP patients have high probability of developing eye tumours. A thorough ophthalmic examination is necessary to establish an early diagnosis.
